Evidence map›Paper›PMID 31388893›Full record

ArticleInternal and emergency medicine2019

New perspectives in eosinophilic granulomatosis with polyangiitis (EGPA): report of the first meeting of the European EGPA Study Group.

Chiara Marvisi, Renato Alberto Sinico, Carlo Salvarani, David Jayne, Domenico Prisco, Benjamin Terrier, Giacomo Emmi, Augusto Vaglio, European EGPA Study Group

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Article in Internal and emergency medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chiara MarvisiUniversity of Modena and Reggio Emilia, and Azienda USL-IRCCS, Reggio Emilia, Italy.
Renato Alberto SinicoDepartment of Medicine and Surgery, University of Milano-Bicocca and ASST Monza, Monza, Italy.
Carlo SalvaraniUniversity of Modena and Reggio Emilia, and Azienda USL-IRCCS, Reggio Emilia, Italy.
David JayneDepartment of Medicine, University of Cambridge, Cambridge, UK.
Domenico PriscoDipartimento Di Medicina Sperimentale e Clinica, Università Di Firenze, Largo Brambilla 3, 50134, Florence, Italy.
Benjamin TerrierDepartment of Internal Medicine, National Referral Center for Rare Systemic and Autoimmune Diseases, Hôpital Cochin, Paris, France.
Giacomo EmmiDipartimento Di Medicina Sperimentale e Clinica, Università Di Firenze, Largo Brambilla 3, 50134, Florence, Italy. giacomo.emmi@unifi.it.
Augusto VaglioSOC Nefrologia E Dialisi, Azienda Ospedaliero-Universitaria Meyer, e Dipartimento Di Scienze Biomediche, Sperimentali e Cliniche "Mario Serio", Università Di Firenze, Viale Pieraccini 6, 50139, Florence, Italy. augusto.vaglio@unifi.it.
European EGPA Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The European Eosinophilic Granulomatosis with Polyangiitis (EGPA) study group first gathered in Firenze in December 2018. The discussion was centred around the clinical and therapeutic needs in EGPA which still remain unmet. Indeed, EGPA is a puzzling and rare disease which shares clinical features with other anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAVs) and hypereosinophilic syndromes (HESs). Some of the recommendations published in 2015 are based on data derived from EGPA-related diseases, rather than from EGPA itself, and therefore need to be updated. Thus, the aim of the meeting was to stimulate ongoing research, to promote collaborative European studies and to define the main issues on which future studies should be focused. Current fields of research on EGPA include potential serological biomarkers of disease activity and of specific organ involvement, possible links between different genetic variants and clinical phenotypes, and new therapeutic perspectives. Herein, we give an overview of the meeting with the goal to stimulate an international collaboration and new points of discussion.

Indexed as

ConsensusEosinophilic GranulomaEuropeGranulomatosis with PolyangiitisHumansANCAEosinophilic granulomatosis with polyangiitisEosinophilsMepolizumabRituximabVasculitis

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.