Evidence map›Paper›PMID 31388864›Full record

ArticleJournal of digital imaging2019

Imager-4D: New Software for Viewing Dynamic PET Scans and Extracting Radiomic Parameters from PET Data.

Steven P Rowe, Lilja B Solnes, Yafu Yin, Grant Kitchen, Martin A Lodge, Nicolas A Karakatsanis, Arman Rahmim, Martin G Pomper, Jeffrey P Leal

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of digital imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

Steven P RoweThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 550 N. Broadway Suite 300, Baltimore, MD, 21205, USA. srowe8@jhmi.edu.
Lilja B SolnesThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 550 N. Broadway Suite 300, Baltimore, MD, 21205, USA.
Yafu YinThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 550 N. Broadway Suite 300, Baltimore, MD, 21205, USA.
Grant KitchenInstitute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD, USA.
Martin A LodgeThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 550 N. Broadway Suite 300, Baltimore, MD, 21205, USA.
Nicolas A KarakatsanisThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 550 N. Broadway Suite 300, Baltimore, MD, 21205, USA.
Arman RahmimThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 550 N. Broadway Suite 300, Baltimore, MD, 21205, USA.
Martin G PomperThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 550 N. Broadway Suite 300, Baltimore, MD, 21205, USA.
Jeffrey P LealThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 550 N. Broadway Suite 300, Baltimore, MD, 21205, USA. jleal1@jhmi.edu.
Johns Hopkins University · USUniversity of British Columbia · CA

Funding

Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI Rosalie Wollett · 1985 to 2026
$208.6M
Training/Dissemination-Resource for Molecular Imaging Agents in Precision MedicineP41EB024495 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI MARTIN G POMPER · 2017 to 2026
$11.8M
NCI NIH HHS P30 CA006973NIBIB NIH HHS P41 EB024495
6 · The paper itself

Abstract

Extensive research is currently being conducted into dynamic positron emission tomography (PET) acquisitions (including dynamic whole-body imaging) as well as extraction of radiomic features from imaging modalities. We describe a new PET viewing software known as Imager-4D that provides a facile means of viewing and analyzing dynamic PET data and obtaining associated quantitative metrics including radiomic parameters. The Imager-4D was programmed in the Java language utilizing the FX extensions. It is executable on any system for which a Java w/FX compliant virtual machine is available. The software incorporates the ability to view and analyze dynamic data acquired with different types of dynamic protocols. For image display, the program maintains a built-in library of 62 different lookup tables with monochromatic and full-color distributions. The Imager-4D provides multiple display layouts and can display fused images. Multiple methods of volume-of-interest (VOI) selection are available. Dynamic analysis features, such as image summation and full Patlak analysis, are also available. The user interface includes window width and level, blending, and zoom functionality. VOI sizes are adjustable and data from VOIs can either be displayed numerically or graphically within the software or exported. An example case of a 50-year-old woman with metastatic colorectal cancer and thyroiditis is included and demonstrates the steps for a user to obtain standard PET parameters, dynamic data, and radiomic features using selected VOIs. The Imager-4D represents a novel PET viewer that allows the user to view dynamic PET data, to derive dynamic and radiomic parameters from that data, and to combine dynamic data with radiomics ("dynomics"). The Imager-4D is available as a free download. This software has the potential to speed the adoption of advanced analysis of dynamic PET data into routine clinical use.

Indexed as

Colorectal NeoplasmsFemaleHumansImage Processing, Computer-AssistedImaging, Three-DimensionalLiverLiver NeoplasmsMiddle AgedPositron-Emission TomographySoftwareThyroiditisDynamic PETDynomicsFDG PETRadiomics

Identifiers

PMID31388864
PMCPMC6841823
OpenAlexW2965102400

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.