Evidence map›Paper›PMID 31388843›Full record

ReviewCurrent pain and headache reports2019

A Comprehensive Review of Trigeminal Neuralgia.

Mark R Jones, Ivan Urits, Ken P Ehrhardt, John N Cefalu, Julia B Kendrick, Daniel J Park, Elyse M Cornett, Alan D Kaye, Omar Viswanath

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current pain and headache reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 5 pooled it
14.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 5 syntheses or guidelines pooled it, 198 citations in OpenAlex.

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  6. Article
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  12. Surgical Options for Cranial Nerve Functional Diseases.Advances and technical standards in neurosurgery · 2026
    Review
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  16. Using Quantitative Masticatory Dysfunction to Inform Pain Management in Trigeminal Neuralgia Through Electromyographic Monitoring.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2025
    Observational
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31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Mark R JonesDepartment of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA, 02215, USA.
Ivan UritsDepartment of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA, 02215, USA. iurits@bidmc.harvard.edu.
Ken P EhrhardtDepartment of Anesthesiology, Louisiana State University Health Science Center, New Orleans, LA, USA.
John N CefaluDepartment of Anesthesiology, Louisiana State University Health Science Center, New Orleans, LA, USA.
Julia B KendrickDepartment of Anesthesiology, Louisiana State University Health Science Center, New Orleans, LA, USA.
Daniel J ParkOchsner Clinic Foundation Medical School, University of Queensland, New Orleans, LA, USA.
Elyse M CornettDepartment of Anesthesiology, Louisiana State University Health Science Center, New Orleans, LA, USA.
Alan D KayeDepartment of Anesthesiology, Louisiana State University Health Science Center, New Orleans, LA, USA.
Omar ViswanathValley Anesthesiology and Pain Consultants, Phoenix, AZ, USA.
Louisiana State University Health Sciences Center New Orleans · USHarvard University · USOchsner Medical Center · USUniversity of Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewTrigeminal neuralgia (TN) is characterized by recurrent attacks of lancinating facial pain in the dermatomal distribution of the trigeminal nerve. TN is rare, affecting 4 to 13 people per 100,000. RECENT

findingsAlthough there remains a debate surrounding the pathogenesis of TN, neurovascular compromise is the most currently accepted theory. Minimal stimulation caused by light touch, talking, or chewing can lead to debilitating pain and incapacitation of the patient. Pain may occur sporadically, though is primarily unilateral in onset. The diagnosis is typically determined clinically. Treatment options include medications, surgery, and complementary approaches. Anti-epileptic and tricyclic antidepressant medications are first-line treatments. Surgical management of patients with TN may be indicated in those who have either failed medical treatment with at least three medications, suffer from intolerable side-effects, or have non-remitting symptoms. Surgical treatment is categorized as either destructive or non-destructive. Deep brain and motor cortex neuro-modulatory stimulation are off label emerging techniques which may offer relief to TN that is otherwise refractory to pharmacological management and surgery. Still, sufficient data has yet to be obtained and more studies are needed.

Indexed as

DecompressionFacial PainHumansNeuralgiaTreatment OutcomeTrigeminal NerveTrigeminal NeuralgiaAnti-convulsantChronic painFacial painMicrovascular decompressionNeuromodulationNeuropathic painTrigeminal neuralgia

Identifiers

PMID31388843
OpenAlexW2964633496

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.