Evidence map›Paper›PMID 31388829›Full record

ArticlePlanta2019

Artificial microRNA-mediated resistance to cucumber green mottle mosaic virus in Nicotiana benthamiana.

Chaoqiong Liang, Jianjun Hao, Jianqiang Li, Barbara Baker, Laixin Luo

Abstract read
PubMed Publisher
In one paragraph

Article in Planta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. RNA silencing: the future potential strategy for engineering virus resistance in plants.Physiology and molecular biology of plants : an international journal of functional plant biology · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. Artificial miRNAs and target-mimics as potential tools for crop improvement.Physiology and molecular biology of plants : an international journal of functional plant biology · 2025
    Review
  9. Article
  10. Review
  11. Article
  12. Understanding tobamovirus-plant interactions: implications for breeding resistance to tomato brown rugose fruit virus.Journal of plant pathology : an international journal of the Italian Phytopathological Society · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Chaoqiong LiangCollege of Plant Protection/Beijing Key Laboratory of Seed Disease Testing and Control, China Agricultural University, Beijing, 100193, China.
Jianjun HaoSchool of Food and Agriculture, The University of Maine, Orono, ME, 04469, USA.
Jianqiang LiCollege of Plant Protection/Beijing Key Laboratory of Seed Disease Testing and Control, China Agricultural University, Beijing, 100193, China.
Barbara BakerDepartment of Plant and Microbial Biology, University of California, Berkeley, Berkeley, CA, 94720, USA. bbaker@berkeley.edu.
Laixin LuoCollege of Plant Protection/Beijing Key Laboratory of Seed Disease Testing and Control, China Agricultural University, Beijing, 100193, China. luolaixin@cau.edu.cn.
China Agricultural University · CNUniversity of California, Berkeley · USUniversity of Maine · US

Funding

China Scholarship Council 201606350070National Key Research and Development Program of China 2017YFD0201601National Science Foundation of China 31371910
6 · The paper itself

Abstract

MAIN

conclusionWe describe a Nicotiana benthamiana system for rapid identification of artificial microRNA (amiRNA) to control cucumber green mottle mosaic virus (CGMMV) disease. Although artificial miRNA technology has been used to control other viral diseases, it has not been applied to reduce severe cucumber green mottle mosaic virus (CGMMV) disease and crop loss in the economically important cucurbits. We used our system to identify three amiRNAs targeting CGMMV RNA (amiR1-CP, amiR4-MP and amiR6-Rep) and show that their expression reduces CGMMV replication and disease in virus-infected plants. This work streamlines the process of generating amiRNA virus-resistant crops and can be broadly applied to identify active antiviral amiRNAs against a broad spectrum of viruses to control disease in diverse crops.

Indexed as

Cucumis sativusDisease ResistanceDNA DamageMicroRNAsNicotianaPlant DiseasesTobamovirusMicroRNAsArtificial microRNACrop protectionCucumber green mottle mosaic virusRNA silencingVirus resistance

Identifiers

PMID31388829
OpenAlexW2965712028

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.