ReviewCurrent pain and headache reports2019
Tramadol Prescription over a 4-Year Period in the USA.
Review in Current pain and headache reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Evaluating tramadol utilization and patterns by county-level social determinants of health characteristics from 2015 to 2022.medRxiv : the preprint server for health sciences · 2025Article
- Tramadol use in U.S. Adults With Commercial Health Insurance, 2005-2021.American journal of preventive medicine · 2024Article
- Article
- Comparative safety of tramadol and other opioids following total hip and knee arthroplasty.BMC geriatrics · 2024Article
- Opioid therapy trajectories of patients with chronic non-cancer pain over 1 year of follow-up after initiation of short-acting opioid formulations.Pain medicine (Malden, Mass.) · 2024Article
- Risk Factors for Respiratory Depression Associated with Tramadol Based on the Global Pharmacovigilance Database (VigiBase).Pharmaceuticals (Basel, Switzerland) · 2024Article
- Patterns of Opioid and Non-Opioid Analgesic Consumption in Patients with Post-COVID-19 Conditions.Journal of clinical medicine · 2023Article
- Risk of Hyponatremia after Tramadol/Acetaminophen Single-Pill Combination Therapy: A Real-World Study Based on the OMOP-CDM Database.Drugs in R&D · 2023Article
- Evolving trends in drug overdose mortality in the USA from 2000 to 2020: an age-period-cohort analysis.EClinicalMedicine · 2023Article
- Correlation Between Opioid Drug Prescription and Opioid-Related Mortality in Spain as a Surveillance Tool: Ecological Study.JMIR public health and surveillance · 2023Article
- Tramadol May Increase Risk of Hip Fracture in Older Adults with Post-Traumatic Osteoarthritis.Journal of personalized medicine · 2023Article
- Medication use quality and safety in older adults: 2020 update.Journal of the American Geriatrics Society · 2022Review
- Comparison of Online Patient Reviews and National Pharmacovigilance Data for Tramadol-Related Adverse Events: Comparative Observational Study.JMIR public health and surveillance · 2022Observational
- Effects of chronic tramadol administration on cognitive flexibility in mice.Psychopharmacology · 2021Article
- Engaging pharmacogenomics in pain management and opioid selection.Pharmacogenomics · 2021Review
- Tramadol-induced hiccups: a case-noncase study in the European pharmacovigilance database.Therapeutic advances in drug safety · 2021Article
- Association of Tramadol Use With Risk of Hip Fracture.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2020Article
- Use of Tramadol or Other Analgesics in Patients Treated in the Emergency Department as a Risk Factor for Opioid Use.Pain research & management · 2020Article
- Quantification of Opioid Prescription Practice Changes Due to Hydrocodone Combination Product Rescheduling in an Academic Pain Clinic.Journal of pain research · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewDeaths associated to tramadol, a synthetic opioid, are rising globally. Herein, we characterize prescription patterns of tramadol relative to other opioids in the USA from 2012 to 2015, by geographic region and physician specialty. RECENT
findingsData on opioid was obtained using Truven Health Analytics MarketScan for the years 2012-2015. Inclusion criteria included subjects living in the USA with ages from 12 to 64 years. Patterns of prescription of tramadol were contrasted with other prescription opioids including hydrocodone, codeine, oxycodone, oxymorphone, methadone, and fentanyl. Between 2012 and 2015, prescriptions for tramadol increased by 22.8%. The absolute rate of prescription varies considerably per region, with tramadol representing nearly 20% of opioid prescriptions in the South, which, in turn, represents nearly 50% of all prescriptions in the USA. Significant differences were seen when comparing prescribers of tramadol with other opioids (p < 0.0001). Tramadol was more frequently prescribed by family practice (40% vs. 32%) and internal medicine physicians (19% vs. 16%). Family medicine, internal medicine, and non-physician prescribers responded by 67.2% of all tramadol prescriptions in 2015. The proportion of patients receiving tramadol from non-physician prescribers increased by 56% between 2012 and 2015 (p < 0.001) IOM. Tramadol prescriptions rates have continuously increased both nationally and throughout all US regions. Important differences exist among regions and physician specialties. These results may be helpful in the creation of regional policies to monitor reasons for this increase and to avoid excessive use of tramadol.
Indexed as
Identifiers
31388761What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.