Evidence map›Paper›PMID 31388719›Full record

ArticleInternational urogynecology journal2020

Aging effects on pelvic floor support: a pilot study comparing young versus older nulliparous women.

Carolyn W Swenson, Mariana Masteling, John O DeLancey, Lahari Nandikanti, Payton Schmidt, Luyun Chen

Open access · greenAbstract read
In one paragraph

Article in International urogynecology journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Female pelvic floor protection-Where do we have to go?Acta obstetricia et gynecologica Scandinavica · 2026
    Review
  3. Article
  4. Review
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  8. [Application of Magnetic Resonance Imaging in the Diagnosis and Treatment of Middle Compartment Defect].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
    Review
  9. Pre- and Post-Surgical MRI Analysis of Levator Ani in Pelvic Organ Prolapse Patients: A Single-Center Study.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Carolyn W SwensonDepartment of Obstetrics and Gynecology, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI, 48109, USA. scarolyn@med.umich.edu.ORCID 0000-0002-3220-9445
Mariana MastelingDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, MI, USA.
John O DeLanceyDepartment of Obstetrics and Gynecology, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI, 48109, USA.
Lahari NandikantiSchool of Public Health, University of Michigan, Ann Arbor, MI, USA.
Payton SchmidtDepartment of Obstetrics and Gynecology, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI, 48109, USA.
Luyun ChenDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
University of Michigan · US

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Neil Alexander · 2004 to 2026
$29.2M
University of Michigan WRHR Career Development ProgramK12HD065257 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FENNER, DEE ELLEN · 2010 to 2019
$3.4M
Michigan Institute for Clinical and Health Research UL1TR002240NCATS NIH HHS UL1 TR002240NIA NIH HHS P30 AG024824NICHD NIH HHS K12 HD065257
6 · The paper itself

Abstract

introduction and hypothesisWe sought to determine age-related changes to the pelvic floor in the absence of childbirth effects.

methodsA case-control study was conducted from June 2017 to August 2018 comparing two groups of nulliparous women: <40 years old and ≥ 70 years old. Clinical evaluation included POP-Q, instrumented speculum testing, and handgrip strength. Dynamic 3D-stress MRI was performed on all women to obtain genital and levator hiatus (LH) lengths, LH area, and levator bowl volume. LH shape was quantified using a novel measure called the "V-U index." Pubovisceral muscle (PVM) cross-sectional area (CSA) was also measured. Bivariate comparisons between the two groups were made for all variables. Effect sizes were calculated for MRI measurements.

resultsTwelve young and 9 older nulliparous women were included. Levator bowl volume at rest was 83% larger in older women (108.0 ± 34.5 cm

conclusionsLevator bowl volume at rest was over 80% larger among older women, reflecting a generalized posterior distension with age.

Indexed as

Pelvic FloorPelvic Organ ProlapseAdultAgedAgingCase-Control StudiesFemaleHand StrengthHumansImaging, Three-DimensionalPilot ProjectsPregnancyUltrasonographyAgingGenital hiatusLevator areaLevator bowl volumeMRIPelvic organ support

Identifiers

PMID31388719
PMCPMC7720445
OpenAlexW2966179898

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.