Evidence map›Paper›PMID 31388590›Full record

ArticleHeliyon2019

Concentration of selected liver enzymes across the stages of glomerular function: the associations with PFOA and PFOS.

Ram B Jain

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Ram B Jain2959 Estate View Ct, Dacula, GA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kidney function/dysfunction may affect liver function/dysfunction and vice versa. Liver function is indicated by the observed concentrations of several liver enzymes. Kidney function is indicated by the glomerular filtration rate. Consequently, it is logical to study associations between liver enzymes and glomerular filtration rate indicted by the stages of glomerular function (GF). Thus, this study was undertaken to evaluate the associations between selected liver enzymes and the stages of GF for US adults aged >= 20 years. Data (N = 9523) for US adults for the years 2003-2014 from National Health and Nutrition Examination Survey were analyzed to estimate variabilities in concentrations associated with liver enzymes alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphate (APH), and γ-glutamyl transferase (GGT) across the stages of GF and to assess variabilities in associations that perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) may have with these enzymes across the stages of GF. Those with eGFR >90 mL/min/1.73 m

Indexed as

ChemistryEnvironmental healthEnvironmental pollutionEnvironmental risk assessmentEnvironmental scienceEnvironmental toxicologyKidneyLiverLiver enzymesNHANESPFAA

Identifiers

PMID31388590
PMCPMC6667701

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.