Evidence map›Paper›PMID 31388342›Full record

ArticleNutrition & metabolism2019

High serum uric acid level is a mortality risk factor in peritoneal dialysis patients: a retrospective cohort study.

Shilong Xiang, Xiaohui Zhang, Xishao Xie, Junni Wang, Qin Zhou, Zhimin Chen, Yaomin Wang, Guangjun Liu, Fei Han, Jianghua Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrition & metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Pooled it
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  5. Lower time-averaged serum uric acid was associated with increased mortality in peritoneal dialysis patients.Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy · 2025
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  7. The significance of follow-up serum uric acid levels in predicting all-cause mortality and cardiovascular mortality in peritoneal dialysis patients.Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shilong Xiang *Kidney Disease Center, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003 China.
Xiaohui Zhang *Kidney Disease Center, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003 China.
Xishao XieKidney Disease Center, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003 China.
Junni WangKidney Disease Center, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003 China.
Qin ZhouKidney Disease Center, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003 China.
Zhimin ChenKidney Disease Center, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003 China.
Yaomin WangKidney Disease Center, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003 China.
Guangjun LiuKidney Disease Center, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003 China.
Fei HanKidney Disease Center, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003 China.
Jianghua ChenKidney Disease Center, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003 China.ORCID 0000-0002-3282-3998

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe results remain controversial with regards to the impact of serum uric acid on clinical outcomes from peritoneal dialysis population. The aim of our study was to investigate the influence of serum uric acid levels on mortality in peritoneal dialysis patients.

methodsData on 9405 peritoneal dialysis patients from the Zhejiang Renal Data system were retrospectively analyzed. All demographic and laboratory data were recorded at baseline. The study cohort was divided into quintiles according to baseline uric acid level (mg/dL): Q1 (< 6.06), Q2 (6.06-6.67), Q3 (6.68-7.27) (reference), Q4 (7.28-8.03), and Q5 (≥8.04). Hazards ratio (HR) of all-cause and cardiovascular mortality was calculated.

resultsMean serum uric acid was 7.07 ± 1.25 mg/dL. During a median follow-up of 29.4 (range, 3.0 to 115.4) months, 1226 (13.0%) patients died, of which 515 (5.5%) died of cardiovascular events. The Kaplan-Meier survival curves showed that patients in the middle uric acid quintile (Q3: 6.68-7.27) exhibited the highest patient and cardiovascular survival rates (log-rank test

conclusionsA higher uric acid level was an independent risk factor for all-cause mortality in peritoneal dialysis patients.

Indexed as

End stage renal diseaseMortalityPeritoneal dialysisUric acid

Identifiers

PMID31388342
PMCPMC6670192

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.