Evidence map›Paper›PMID 31388267›Full record

ArticleIndian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion2019

Polyneuropathy Associated with Severe Iron Overload and Oxidative Stress in β-Thalassemia Patients.

Mona H El-Tagui, Khaled M Salama, Mohamed H El-Sabbagh, Eman R Youness, Marwa Ragaey, Amina Abdel-Salam

Open access · bronzeAbstract read
In one paragraph

Article in Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. The Macrophage Iron Signature in Health and Disease.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mona H El-Tagui1Department of Pediatrics, Cairo University, Ali Ibrahim St., Cairo, Egypt.
Khaled M Salama1Department of Pediatrics, Cairo University, Ali Ibrahim St., Cairo, Egypt.
Mohamed H El-SabbaghDepartment of Pediatrics and Neurophysiology, National Institute of Neuromotor System, Cairo, Egypt.
Eman R Youness3Department of Medical Biochemistry, National Research Centre (NRC), Giza, Egypt.
Marwa RagaeyDepartment of Pediatrics and Neurophysiology, National Institute of Neuromotor System, Cairo, Egypt.
Amina Abdel-Salam1Department of Pediatrics, Cairo University, Ali Ibrahim St., Cairo, Egypt.ORCID 0000-0003-0859-2306
Cairo University · EGThe National Institute of Neuromotor System · EGNational Research Centre · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate the frequency of peripheral neuropathy in patients with β-thalassemia, and to assess its relation to iron overload and oxidative stress. Sixty β-thalassemia patients with mean age of 19 ± 4.9 years were recruited. Serum ferritin was quantitatively assessed by enzyme-linked immunoassay and biomarkers of oxidative stress were estimated calorimetrically. Electrophysiological studies using NEMUS 2, Galileu Software were carried out. The patients were separated into two groups: those with abnormal nerve conduction studies (NCS) {Group A; N = 38} and those with normal NCS {Group B; N = 22}. Thirty-eight (63.3%) patients had axonal motor neuropathy as evidenced by abnormal NCS (group A), they showed higher mean serum ferritin (

Indexed as

Iron overloadOxidative stress-β-ThalassemiaPolyneuropathy

Identifiers

PMID31388267
PMCPMC6646492
OpenAlexW2900991171

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.