ArticleNature communications2019
Cytokinin functions as an asymmetric and anti-gravitropic signal in lateral roots.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
51 citing papers in PubMed, 103 citations in OpenAlex.
- Lateral Root Development: Molecular Mechanisms and Adaptive Regulation.Plant, cell & environment · 2026Review
- Article
- Environmental regulation of root growth angle in cereal crops.Plant and soil · 2026Review
- Comparative RNA sequencing-based transcriptome profiling of Quercur robur: specific sets of genes involved in taproot and lateral roots emergence.Tree physiology · 2025Article
- Foraging for water by MIZ1-mediated antagonism between root gravitropism and hydrotropism.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Roles of hormones in regulating root growth-water interactions.Journal of experimental botany · 2025Review
- Spiral phyllotaxis predicts left-right asymmetric growth and style deflection in mirror-image flowers of Cyanella alba.Nature communications · 2025Article
- The asymmetry engine: how plants harness asymmetries to shape their bodies.The New phytologist · 2025Review
- ClearDepth: a simple, robust, and low-cost method to assess root depth in soil.The Plant journal : for cell and molecular biology · 2025Article
- Over 25 years of decrypting PIN-mediated plant development.Nature communications · 2024Review
- Cytokinins regulate spatially specific ethylene production to control root growth in Arabidopsis.Plant communications · 2024Article
- Transcriptomic Insights into Salt Stress Response in Two Pepper Species: The Role of MAPK and Plant Hormone Signaling Pathways.International journal of molecular sciences · 2024Article
- Molecular mechanism of brassinosteroids involved in root gravity response based on transcriptome analysis.BMC plant biology · 2024Article
- Long-term root electrotropism reveals habituation and hysteresis.Plant physiology · 2024Article
- Identification of mebendazole as an ethylene signaling activator reveals a role of ethylene signaling in the regulation of lateral root angles.Cell reports · 2024Article
- CEP hormones at the nexus of nutrient acquisition and allocation, root development, and plant-microbe interactions.Journal of experimental botany · 2024Review
- Fine-tuned nitric oxide and hormone interface in plant root development and regeneration.Journal of experimental botany · 2023Review
- Antigravitropic PIN polarization maintains non-vertical growth in lateral roots.Nature plants · 2023Article
- PIN phospho-regulation drives gravity-dependent non-vertical growth in Arabidopsis roots.Nature plants · 2023Article
- Article
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Authors and funding
14 authors at 6 institutions in 5 countries.
Funding
Abstract
Directional organ growth allows the plant root system to strategically cover its surroundings. Intercellular auxin transport is aligned with the gravity vector in the primary root tips, facilitating downward organ bending at the lower root flank. Here we show that cytokinin signaling functions as a lateral root specific anti-gravitropic component, promoting the radial distribution of the root system. We performed a genome-wide association study and reveal that signal peptide processing of Cytokinin Oxidase 2 (CKX2) affects its enzymatic activity and, thereby, determines the degradation of cytokinins in natural Arabidopsis thaliana accessions. Cytokinin signaling interferes with growth at the upper lateral root flank and thereby prevents downward bending. Our interdisciplinary approach proposes that two phytohormonal cues at opposite organ flanks counterbalance each other's negative impact on growth, suppressing organ growth towards gravity and allow for radial expansion of the root system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.