Evidence map›Paper›PMID 31387941›Full record

ArticleThe Journal of cell biology2019

α-Integrins dictate distinct modes of type IV collagen recruitment to basement membranes.

Ranjay Jayadev, Qiuyi Chi, Daniel P Keeley, Eric L Hastie, Laura C Kelley, David R Sherwood

Abstract read
In one paragraph

Article in The Journal of cell biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 82 citations in OpenAlex.

  1. Article
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  7. Basement membranes at a glance.Journal of cell science · 2025
    Review
  8. Article
  9. The life cycle of type IV collagen.Matrix biology : journal of the International Society for Matrix Biology · 2025
    Review
  10. Divergent Functions of Rap1A and Rap1B in Endothelial Biology and Disease.International journal of molecular sciences · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ranjay JayadevDepartment of Biology, Regeneration Next, Duke University, Durham, NC.
Qiuyi ChiDepartment of Biology, Regeneration Next, Duke University, Durham, NC.
Daniel P KeeleyDepartment of Biology, Regeneration Next, Duke University, Durham, NC.
Eric L HastieDepartment of Biology, Regeneration Next, Duke University, Durham, NC.
Laura C KelleyDepartment of Biology, Regeneration Next, Duke University, Durham, NC.ORCID 0000-0003-2706-3610
David R SherwoodDepartment of Biology, Regeneration Next, Duke University, Durham, NC david.sherwood@duke.edu.ORCID 0000-0002-4448-6917
Duke University · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Understanding how cells invade through basement membrane in vivoR35GM118049 · NIGMS · DUKE UNIVERSITY · PI David R Sherwood · 2016 to 2026
$6.8M
Visualizing and Elucidating the Role of Force on Type IV Collagen in DevelopmentR21HD084290 · NICHD · DUKE UNIVERSITY · PI SHERWOOD, DAVID R · 2016 to 2017
$412k
NICHD NIH HHS R21 HD084290NIGMS NIH HHS R35 GM118049NIH HHS P40 OD010440
6 · The paper itself

Abstract

Basement membranes (BMs) are cell-associated extracellular matrices that support tissue integrity, signaling, and barrier properties. Type IV collagen is critical for BM function, yet how it is directed into BMs in vivo is unclear. Through live-cell imaging of endogenous localization, conditional knockdown, and misexpression experiments, we uncovered distinct mechanisms of integrin-mediated collagen recruitment to

Indexed as

AnimalsBasement MembraneCaenorhabditis elegansCaenorhabditis elegans ProteinsCollagen Type IVIntegrin beta ChainsCaenorhabditis elegans ProteinsCollagen Type IVIntegrin beta Chainspat-3 protein, C elegans

Identifiers

PMID31387941
PMCPMC6719451
OpenAlexW2966340596

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.