Evidence map›Paper›PMID 31387908›Full record

ArticlemBio2019

Transposon Mutagenesis in Chlamydia trachomatis Identifies CT339 as a ComEC Homolog Important for DNA Uptake and Lateral Gene Transfer.

Scott D LaBrie, Zoë E Dimond, Kelly S Harrison, Srishti Baid, Jason Wickstrum, Robert J Suchland, P Scott Hefty

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
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  5. Complete deletion of theInfection and immunity · 2025
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  8. Journal of bacteriology · 2025
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  9. Recognition ofInfection and immunity · 2024
    Article
  10. Review
  11. Review
  12. Infection and immunity · 2024
    Article
  13. Article
  14. Type III Secretion inMicrobiology and molecular biology reviews : MMBR · 2023
    Review
  15. Article
  16. Molecular pathogenesis ofFrontiers in cellular and infection microbiology · 2023
    Review
  17. Advances in genetic manipulation ofFrontiers in immunology · 2023
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Scott D LaBrieDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA.
Zoë E DimondDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA.
Kelly S HarrisonDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA.
Srishti BaidDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA.
Jason WickstrumDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA.
Robert J SuchlandDepartment of Medicine, University of Washington-Seattle, Seattle, Washington, USA.
P Scott HeftyDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA pshefty@ku.edu.
University of Kansas · USUniversity of Washington · US

Funding

Synthetic Chemical Biology CoreP20GM113117 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI OROZCO, ROBIN C. · 2016 to 2025
$23.9M
Understanding the mechanobiology of stem cells in a microengineered 3D cardiac tissue environment with cardiomyopathyP20GM103638 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI HOLMSTROM, ERIK D · 2012 to 2021
$22.1M
Functional genomics for ChlamydiaR01AI126785 · NIAID · UNIVERSITY OF WASHINGTON · PI HEFTY, P SCOTT, HYBISKE, KEVIN · 2016 to 2025
$7.1M
Transposon mutagenesis for Chlamydia trachomatisR21AI125929 · NIAID · UNIVERSITY OF KANSAS LAWRENCE · PI HEFTY, P SCOTT · 2016 to 2017
$407k
NIAID NIH HHS R01 AI126785NIAID NIH HHS R21 AI125929NIGMS NIH HHS P20 GM103638NIGMS NIH HHS P20 GM113117
6 · The paper itself

Abstract

Transposon mutagenesis is a widely applied and powerful genetic tool for the discovery of genes associated with selected phenotypes.

Indexed as

Gene Transfer, HorizontalAnimalsBacterial ProteinsChlamydia InfectionsChlamydia trachomatisDNA, BacterialDNA Transposable ElementsFemaleHumansMiceMice, Inbred C57BLMutagenesis, InsertionalMutationBacterial ProteinsDNA, BacterialDNA Transposable ElementsChlamydia trachomatisgenetic competencemutagenesistransposons

Identifiers

PMID31387908
PMCPMC6686042
OpenAlexW2966309307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.