Evidence map›Paper›PMID 31387901›Full record

ArticlemBio2019

Regulation of Iron Storage by CsrA Supports Exponential Growth of Escherichia coli.

Christine Pourciau, Archana Pannuri, Anastasia Potts, Helen Yakhnin, Paul Babitzke, Tony Romeo

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Multitier regulation of theJournal of bacteriology · 2024
    Article
  6. Article
  7. Pathogenicity and identification of host adaptation genes of the avian pathogenicFrontiers in cellular and infection microbiology · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Battle for Metals: Regulatory RNAs at the Front Line.Frontiers in cellular and infection microbiology · 2022
    Review
  14. Article
  15. Article
  16. Article
  17. Bacterial iron detoxification at the molecular level.The Journal of biological chemistry · 2020
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Christine PourciauDepartment of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, Florida, USA.
Archana PannuriDepartment of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, Florida, USA.
Anastasia PottsDepartment of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, Florida, USA.
Helen YakhninDepartment of Biochemistry and Molecular Biology, Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania, USA.
Paul BabitzkeDepartment of Biochemistry and Molecular Biology, Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania, USA.ORCID 0000-0003-2481-1062
Tony RomeoDepartment of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, Florida, USA tromeo@ufl.edu.
University of Florida · USPennsylvania State University · US

Funding

Mechanism of CsrA-mediated global regulationR01GM059969 · NIGMS · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI BABITZKE, PAUL L, ROMEO, TONY · 1999 to 2021
$7.6M
NIGMS NIH HHS R01 GM059969
6 · The paper itself

Abstract

The global regulatory protein CsrA coordinates gene expression in response to physiological cues reflecting cellular stress and nutrition. CsrA binding to the 5' segments of mRNA targets affects their translation, RNA stability, and/or transcript elongation. Recent studies identified probable mRNA targets of CsrA that are involved in iron uptake and storage in

Indexed as

Bacterial ProteinsCarrier ProteinsCytochrome b GroupEscherichia coliEscherichia coli ProteinsFerritinsGene Expression Regulation, BacterialHydrogen PeroxideIronRepressor ProteinsRNA-Binding ProteinsBacterial ProteinsbacterioferritinCarrier ProteinsCsrA protein, E coliCytochrome b GroupEscherichia coli ProteinsFerritinsHydrogen PeroxideIronRepressor ProteinsRNA-Binding ProteinsSufA protein, E colibacterial growthCsrACsrBCsrCferritiniron homeostasisiron storage proteinsoxidative stressposttranscriptional regulationRNA binding proteinssRNAsstress responses

Identifiers

PMID31387901
PMCPMC6686035
OpenAlexW2965135697

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.