Evidence map›Paper›PMID 31387880›Full record

ArticleBlood advances2019

Clonal expansion of CAR T cells harboring lentivector integration in the CBL gene following anti-CD22 CAR T-cell therapy.

Nirali N Shah, Haiying Qin, Bonnie Yates, Ling Su, Haneen Shalabi, Mark Raffeld, Mark A Ahlman, Maryalice Stetler-Stevenson, Constance Yuan, Shuang Guo and 4 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Blood advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

103 citing papers in PubMed, 1 synthesis or guideline pooled it, 144 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Nonclinical safety assessment of SBT777101, a CAR-engineered regulatory T cell therapy for autoimmune diseases.Toxicological sciences : an official journal of the Society of Toxicology · 2026
    Article
  6. Review
  7. Review
  8. Emerging strategies to reduce the side effects of CAR-T cell therapy: focusing on gene editing and nanotechnology.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  9. Article
  10. Article
  11. Review
  12. Isolated oral CD30Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  13. Article
  14. Review
  15. Review
  16. Robust CD4medRxiv : the preprint server for health sciences · 2025
    Article
  17. Review
  18. Review
  19. Review
  20. Review

43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Nirali N ShahPediatric Oncology Branch, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD.ORCID 0000-0002-8474-9080
Haiying QinPediatric Oncology Branch, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD.
Bonnie YatesPediatric Oncology Branch, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD.
Ling SuCancer Research Technology Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD.
Haneen ShalabiPediatric Oncology Branch, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD.
Mark RaffeldMolecular Diagnostics Section, Laboratory of Pathology, Center for Cancer Research, NCI, NIH, Bethesda, MD.
Mark A AhlmanRadiology and Imaging Sciences, NIH Clinical Center, Bethesda, MD.
Maryalice Stetler-StevensonFlow Cytometry, Department of Pathology, NCI, NIH, Bethesda, MD.
Constance YuanFlow Cytometry, Department of Pathology, NCI, NIH, Bethesda, MD.ORCID 0000-0002-2601-3665
Shuang GuoCancer Research Technology Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD.
Siyuan LiuCancer Research Technology Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD.
Stephen H HughesHIV Dynamics and Replication Program, NCI, NIH, Frederick, MD.ORCID 0000-0002-9176-4377
Terry J FryPediatric Oncology Branch, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD.ORCID 0000-0001-8044-5226
Xiaolin WuCancer Research Technology Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD.ORCID 0000-0002-6432-1300
National Institutes of Health · USLeidos (United States) · USCenter for Cancer Research · USNational Institutes of Health Clinical Center · US

Funding

NCI NIH HHS HHSN261200800001E
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell Culture TechniquesGene ExpressionImmunotherapy, AdoptiveFemaleGenetic VectorsHumansLentivirusPositron-Emission TomographyPrecursor B-Cell Lymphoblastic Leukemia-LymphomaProto-Oncogene Proteins c-cblSialic Acid Binding Ig-like Lectin 2T-LymphocytesTransduction, GeneticTransgenesTreatment OutcomeCBL protein, humanProto-Oncogene Proteins c-cblSialic Acid Binding Ig-like Lectin 2

Identifiers

PMID31387880
PMCPMC6693002
OpenAlexW2964464562

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.