Evidence map›Paper›PMID 31387775›Full record

ArticleAnnals of epidemiology2019

Perceived racism in relation to telomere length among African American women in the Black Women's Health Study.

Darlene Lu, Julie R Palmer, Lynn Rosenberg, Alexandra E Shields, Esther H Orr, Immaculata DeVivo, Yvette C Cozier

Open access · greenAbstract read
In one paragraph

Article in Annals of epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 4 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 4 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Racial/Ethnic Discrimination and Cardiometabolic Diseases: A Systematic Review.Journal of racial and ethnic health disparities · 2024
    Pooled it
  2. Pooled it
  3. Racism and Older Black Americans' Health: a Systematic Review.Journal of urban health : bulletin of the New York Academy of Medicine · 2022
    Pooled it
  4. Pooled it
  5. Article
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  11. Inequities in the Impacts of Hurricanes and Other Extreme Weather Events for Cancer Survivors.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Review
  12. Review
  13. Article
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  15. Health Effects of Policing in Hospitals: a Narrative Review.Journal of racial and ethnic health disparities · 2023
    Review
  16. Review
  17. Article
  18. Trauma and US Minority Children and Youth.Current psychiatry reports · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Darlene LuDepartment of Biostatistics, Boston University School of Public Health, Boston, MA; Slone Epidemiology Center at Boston University, Boston, MA.
Julie R PalmerSlone Epidemiology Center at Boston University, Boston, MA; Department of Epidemiology, Boston University School of Public Health, Boston, MA.
Lynn RosenbergSlone Epidemiology Center at Boston University, Boston, MA; Department of Epidemiology, Boston University School of Public Health, Boston, MA.
Alexandra E ShieldsDepartment of Medicine, Harvard Medical School, Boston, MA; Harvard/MGH Center on Genomics, Vulnerable Populations, and Health Disparities, Massachusetts General Hospital, Boston, MA.
Esther H OrrBrigham and Women's Hospital, Boston, MA; Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.
Immaculata DeVivoProgram in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.
Yvette C CozierSlone Epidemiology Center at Boston University, Boston, MA; Department of Epidemiology, Boston University School of Public Health, Boston, MA. Electronic address: yvettec@bu.edu.
Boston University · USHarvard University · USMassachusetts General Hospital · US

Funding

A Follow-up Study for Causes of Cancer in Black WomenU01CA164974 · NCI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Kimberly A. Bertrand, Yvette C Cozier · 2017 to 2026
$24.0M
FOLLOW-UP STUDY FOR CAUSES OF ILLNESS IN BLACK WOMENR01CA058420 · NCI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ROSENBERG, LYNN · 1999 to 2013
$20.7M
A Follow-up Study for Causes of Cancer in Black WomenUM1CA164974 · NCI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ROSENBERG, LYNN · 2012 to 2017
$13.7M
NCI NIH HHS R01 CA058420NCI NIH HHS U01 CA164974NCI NIH HHS UM1 CA164974
6 · The paper itself

Abstract

purposeTelomere length is considered a biomarker of human aging and premature morbidity and mortality which has been associated with chronic stress.

methodsWe assessed the relation between perceived racism and telomere length in the Black Women's Health Study, a follow-up study of U.S. black women begun in 1995. Participants were asked about frequency of "everyday racism" (e.g., "people act as if they think you are not intelligent") and "institutional racism" (e.g., "ever treated unfairly due to race by police"). Using quantitative real-time polymerase chain reaction assay, relative telomere lengths (RTL) were measured as the copy number ratio of telomere repeat to a single control gene in 997 participants. Associations of racism variables with log-RTL were estimated by multivariable linear regression, with adjustment for age at blood draw and potential confounders.

resultsParticipants were aged 40-70 years (mean = 55.6 years), and mean telomere length was 0.77 (range 0.21-1.38). In stratified analyses, there was an inverse association between everyday racism and log-RTL among women who did not discuss their experiences of racism with others (β = -0.1104; 95% CI = -0.2140 to -0.0067; P = .045).

conclusionsEveryday racism was associated with shorter telomere length among women who reported not discussing those experiences with others.

Indexed as

AdultAgedBlack or African AmericanFemaleHumansLeukocytesMiddle AgedPrejudiceRacismReal-Time Polymerase Chain ReactionSurveys and QuestionnairesTelomereTelomere ShorteningWomen's HealthAfrican AmericanBlackBlack Women's Health StudyLeukocyte telomere lengthRacismWomen

Identifiers

PMID31387775
PMCPMC7048405
OpenAlexW2952353013

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.