Evidence map›Paper›PMID 31387769›Full record

ArticlePsychiatry research2019

Sleep problems and attenuated psychotic symptoms in youth at clinical high-risk for psychosis.

Katrina B Goines, Allison M LoPilato, Jean Addington, Carrie E Bearden, Kristin S Cadenhead, Tyrone D Cannon, Barbara A Cornblatt, Daniel H Mathalon, Thomas H McGlashan, Diana O Perkins and 3 more

Open access · greenAbstract read
In one paragraph

Article in Psychiatry research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 2 countries.

Katrina B GoinesDepartment of Psychology, Emory University, 36 Eagle Row, Atlanta, GA 30322, USA. Electronic address: katrina.goines@emory.edu.
Allison M LoPilatoDepartment of Psychiatry and Behavioral Sciences, Emory School of Medicine, Atlanta, GA, USA; Department of Psychology, Emory University, 36 Eagle Row, Atlanta, GA 30322, USA.
Jean AddingtonDepartment of Psychiatry, University of Calgary, Calgary, AB, Canada.
Carrie E BeardenSemel Institute for Neuroscience and Human Behavior & Department of Psychology, University of California, Los Angeles, USA.
Kristin S CadenheadDepartment of Psychiatry, UCSD, San Diego, CA, USA.
Tyrone D CannonDepartment of Psychiatry, Yale University, New Haven, CT, USA; Department of Psychology, Yale University, New Haven, CT, USA.
Barbara A CornblattDepartment of Psychiatry, Zucker Hillside Hospital, New York City, NY, USA.
Daniel H MathalonDepartment of Psychiatry, UCSF, San Francisco, CA, USA; San Francisco VA Medical Center, San Francisco, CA, USA.
Thomas H McGlashanDepartment of Psychiatry, Yale University, New Haven, CT, USA.
Diana O PerkinsDepartment of Psychiatry, University of North Carolina, Chapel Hill, NC, USA.
Ming T TsuangDepartment of Psychiatry, UCSD, San Diego, CA, USA.
Scott W WoodsDepartment of Psychiatry, Yale University, New Haven, CT, USA.
Elaine F WalkerDepartment of Psychiatry and Behavioral Sciences, Emory School of Medicine, Atlanta, GA, USA; Department of Psychology, Emory University, 36 Eagle Row, Atlanta, GA 30322, USA.
Emory University · USYale University · USUniversity of California, San Diego · USSan Francisco VA Medical Center · USUniversity of Calgary · CAUniversity of California, Los Angeles · USUniversity of North Carolina at Chapel Hill · USZucker Hillside Hospital · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
1/9 Predictors and Mechanisms of Conversion to PsychosisU01MH081902 · NIMH · YALE UNIVERSITY · PI CANNON, TYRONE D · 2008 to 2018
$12.4M
5/9 Predictors and Mechanisms of Conversion to PsychosisU01MH082004 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PERKINS, DIANA O. · 2008 to 2018
$7.5M
Administrative Supplement Harmonization of At Risk Multisite Observational Networks for Youth(HARMONY)U01MH081928 · NIMH · BETH ISRAEL DEACONESS MEDICAL CENTER · PI STONE, WILLIAM SETH · 2008 to 2018
$7.1M
4/9-Predictors and Mechanisms of Conversion to PsychosisU01MH081857 · NIMH · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI CORNBLATT, BARBARA A. · 2008 to 2018
$6.2M
8/9 Predictors and Mechanisms of Conversion to PsychosisU01MH082022 · NIMH · YALE UNIVERSITY · PI WOODS, SCOTT W · 2008 to 2018
$6.0M
2/9 - Predictors and Mechanisms of Conversion to PsychosisU01MH081988 · NIMH · EMORY UNIVERSITY · PI WALKER, ELAINE FRAN · 2008 to 2018
$5.4M
6/9-Predictors and Mechanisms of Conversion to PsychosisU01MH081944 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CADENHEAD, KRISTIN S. · 2008 to 2018
$4.9M
"7/9" Predictors and Mechanisms of Conversion to PsychosisU01MH081984 · NIMH · UNIVERSITY OF CALGARY · PI ADDINGTON, JEAN M · 2008 to 2018
$4.2M
9/9-Predictors and Mechanisms of Conversion to PsychosisU01MH076989 · NIMH · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI MATHALON, DANIEL H · 2014 to 2018
$3.9M
Functional Brain Abnormalities in the Schizophrenia ProdromeR01MH076989 · NIMH · YALE UNIVERSITY · PI MATHALON, DANIEL H · 2007 to 2014
$2.3M
NCATS NIH HHS UL1 TR001863NIMH NIH HHS R01 MH076989NIMH NIH HHS U01 MH076989NIMH NIH HHS U01 MH081857NIMH NIH HHS U01 MH081902NIMH NIH HHS U01 MH081928NIMH NIH HHS U01 MH081944NIMH NIH HHS U01 MH081984NIMH NIH HHS U01 MH081988NIMH NIH HHS U01 MH082004NIMH NIH HHS U01 MH082022
6 · The paper itself

Abstract

There has been growing interest on the effect of sleep problems on psychotic and prodromal symptoms. The current study investigated cross-sectional relations between sleep problems and attenuated psychotic symptoms in a large sample of 740 youth at Clinical High Risk (CHR) for psychosis in an attempt to replicate previous findings and assess whether findings from general population samples and psychotic samples extend to this CHR sample. Sleep problems were found to be significantly positively associated with attenuated psychotic symptom severity. Sleep problems were also found to be more closely associated with certain specific prodromal symptoms (e.g., suspiciousness and perceptual abnormalities) than other attenuated psychotic symptoms. Further, we found that depression mediated the cross-sectional association between sleep problems and paranoid symptoms only. This adds to a growing body of evidence suggesting the mediation role of depression is more pronounced for paranoid-type psychotic symptoms as compared to other psychotic symptoms (e.g., hallucinations).

Indexed as

AdolescentCross-Sectional StudiesDepressionFemaleHumansMaleProdromal SymptomsPsychotic DisordersRisk FactorsSleep Wake DisordersCHRInsomniaProdromalProdromeSchizophrenia-spectrum

Identifiers

PMID31387769
PMCPMC6888892
OpenAlexW2964776338

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.