ArticleBMC oral health2019
Evaluation of antibacterial activity of propolis on regenerative potential of necrotic immature permanent teeth in dogs.
Article in BMC oral health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Tissue Characteristics in Endodontic Regeneration: A Systematic Review.International journal of molecular sciences · 2022Pooled it
- Effect of Chitosan Nanoparticles as an Irrigant in Regenerative Endodontic Therapy of Necrotic Immature Permanent Teeth: An In Vivo Dog Model Study.Biomedicines · 2026Article
- Antimicrobial effects of Propolis, calcium Hydroxide, triple antibiotic paste, and modified triple antibiotic paste on tubular dentin inoculated with a dual-species biofilm: an ex vivo study.BMC oral health · 2026Article
- Synergistic antibiofilm activity of methylene blue and silver nanoparticle-mediated photothermal therapy against Enterococcus faecalis biofilm.Scientific reports · 2025Article
- Effect of Chitosan and bioactive glass nanomaterials as intracanal medicaments on TGF-β1 release from intraradicular dentin.BMC oral health · 2025Article
- Therapeutic Potential of Propolis in Preclinical Models of Cancer and Infectious Diseases: A Review.International journal of molecular sciences · 2025Review
- Antimicrobial Properties of Hive Products and Their Potential Applications in Human and Veterinary Medicine.Antibiotics (Basel, Switzerland) · 2025Review
- Efficacy of non -thermal pressure plasma versus other modalities for disinfection of primary root canals.BMC oral health · 2025Article
- Regenerative endodontic therapy in immature teeth using photobiomodulation and photodynamic therapy; a histomorphological study in canine model.BMC oral health · 2024Article
- Histological evaluation of the regenerative potential of injectable hyaluronic acid hydrogel or collagen with blood clot as scaffolds during revascularization of immature necrotic dog's teeth.Open veterinary journal · 2024Article
- Regenerative potential of mesoporous silica nanoparticles scaffold on dental pulp and root maturation in immature dog's teeth: a histologic and radiographic study.BMC oral health · 2024Article
- Effect of microbubble as local drug delivery system in endodontic management - AnThe Saudi dental journal · 2024Article
- Biocompatibility of mineral trioxide aggregate and biodentine as root-end filling materials: an in vivo study.Scientific reports · 2024Article
- Article
- Unlocking the Potential of Cellular Guidance in Endodontics: Advancing the Process of Pulp Regeneration and Beyond.Cureus · 2024Review
- A Potential Intracanal Medicament, 2-Hydroxyisocaproic Acid (HICA): Cytotoxicity, Genotoxicity, and Its Effect on SCAP Differentiation.Dentistry journal · 2023Article
- Efficacy of propolis and triple antibiotic paste as intra-canal medicaments for revascularisation of immature teeth in dogs: a comparative study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2023Article
- Regenerative endodontic therapy in mature teeth with necrotic pulp and apical periodontitis using two disinfection protocols.BMC oral health · 2023Article
- Expert consensus on regenerative endodontic procedures.International journal of oral science · 2022Review
- Clinical Outcome and Comparison of Regenerative and Apexification Intervention in Young Immature Necrotic Teeth-A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2022Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study evaluated the antibacterial efficiency and ability of propolis to promote regeneration of immature permanent non-vital dogs' teeth.
methodsNinety six immature permanent premolars teeth in 6 mongrel dogs were divided randomly into: experimental teeth (N = 72) and control teeth (N = 24). Periapical pathosis was induced in all experimental and positive control teeth. Experimental teeth were classified according to the used intra-canal medication into: group I (N = 36), propolis paste was used and group II (N = 36), triple antibiotic paste (TAP) was used. Bacteriologic samplings were collected before and after exposure to intra-canal medicaments. After the disinfection period (3 weeks), revascularization was induced in all experimental teeth. Each group was subdivided according to the root canal orifice plug into: subgroup A (N = 18), propolis paste was used and subgroup B (N = 18), mineral trioxide aggregates (MTA) was used. Each subgroup was further subdivided according to the evaluation period into 3 subdivisions (6 teeth each): subdivision 1; after 2 weeks, subdivision 2; after one month and subdivision 3; after 2 months. Positive control group had 12 teeth with induced untreated periapical pathosis. Negative control group had 12 untouched sound teeth. All teeth were evaluated with radiography and histology. The bacteriologic and radiographic data were analyzed using repeated measures ANOVA and post-hoc Tukey tests. The histologic data were analyzed using Kruskal-Wallis test, Mann-Whitney U test with Bonferroni's adjustment and Chi-square test. The significance level was set at P ≤ .05.
resultsThere was no significant difference in the antibacterial effectiveness between TAP and propolis groups (P > .05). In all subdivisions, there was no significant difference between the experimental groups in terms of increase in root length and dentin thickness, decrease in apical closure, new hard tissue formation, vital tissue formation inside the pulp canal and apical closure scores (P > .05).
conclusionPropolis can be comparable with TAP as a disinfection treatment option in regenerative endodontic. As a root canal orifice plug after revascularization of necrotic immature permanent teeth in dogs, propolis induces a progressive increase in root length and dentin thickness and a decrease in apical diameter similar to those of MTA.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.