ArticleBMC cancer2019
Oncologic outcome of marginal mandibulectomy in squamous cell carcinoma of the lower gingiva.
Article in BMC cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 37 citations in OpenAlex.
- Induction chemotherapy combined with immunotherapy in locally advanced head and neck squamous cell carcinoma.BMC cancer · 2021Trial
- A Real-World Analysis of Oncological Outcomes in Patients with Oral Squamous Cell Carcinoma Requiring Marginal Mandibulectomy for Achieving Clear Surgical Margins.South Asian journal of cancer · 2025Article
- Oncological Safety and Feasibility of Posterior Marginal Mandibulectomy vis-à-vis Anterior Marginal Mandibulectomy in Oral Cancers.South Asian journal of cancer · 2025Article
- Prognosis, Controversies and Assessment of Bone Erosion or Invasion of Oral Squamous Cell Carcinoma.Diagnostics (Basel, Switzerland) · 2025Review
- Sentinel lymph node biopsy provides better regional control than observation in early stage maxillary squamous cell carcinoma.Frontiers in oncology · 2025Article
- Risk factors for local recurrence following marginal mandibulectomy in gingival cancer.Scientific reports · 2024Article
- Clinicopathological analysis of 134 patients with squamous cell carcinoma of the mandibular gingiva.Heliyon · 2024Article
- Factors associated with survival and patient's quality of life after segmental mandibulectomy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
- Nomograms for Predicting Cancer-Specific Survival of Patients with Gingiva Squamous Cell Carcinoma: A Population-Based Study.Current medical science · 2021Article
- Central neck lymph node metastasis in oral squamous cell carcinoma at the floor of mouth.BMC cancer · 2021Article
- Nonsmoking and Nondrinking Oral Squamous Cell Carcinoma Patients: A Different Entity.Frontiers in oncology · 2021Article
- Impact of Oral Hygiene on Prognosis in Patients With Squamous Cell Carcinoma of the Lower Gingiva.Frontiers in surgery · 2021Article
- Effect of Blood Transfusion on Short- and Long-Term Outcomes in Oral Squamous Cell Carcinoma Patients Undergoing Free Flap Reconstruction.Frontiers in surgery · 2021Article
- Survival Significance of Number of Positive Lymph Nodes in Oral Squamous Cell Carcinoma Stratified by p16.Frontiers in oncology · 2021Article
- Article
- Immunohistochemical Investigation of Predictive Biomarkers for Mandibular Bone Invasion in Oral Squamous Cell Carcinoma.Pathology oncology research : POR · 2020Article
- Elective neck dissection versus wait-and-see policy in cT1N0 buccal squamous cell carcinoma.BMC cancer · 2020Article
- Significance of SUV Max for Predicting Occult Lymph Node Metastasis and Prognosis in Early-Stage Tongue Squamous Cell Carcinoma.Journal of oncology · 2020Article
- Predictive Value of Occult Metastasis and Survival Significance of Metabolic Tumor Volume Determined by PET-CT in cT1-2N0 Squamous Cell Carcinoma of the Tongue.Frontiers in oncology · 2020Article
- Comparison Between PET-CT-Guided Neck Dissection and Elective Neck Dissection in cT1-2N0 Tongue Squamous Cell Carcinoma.Frontiers in oncology · 2020Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is a large amount of controversy about the best management of the mandible in oral squamous cell carcinoma (SCC), mainly owing to the inability to acquire accurate bone invasion status. Therefore, our goal was to analyse the oncologic safety in patients undergoing marginal mandibulectomy (MM) for cT1-2 N0 SCC of the lower gingiva.
methodsPatients undergoing MM for untreated cT1-2 N0 SCC of the lower gingiva were retrospectively enrolled. The main endpoints of interest were locoregional control (LRC) and disease-specific survival (DSS).
resultsA total of 142 patients were included in the analysis, and a pathologic positive node was noted in 27 patients. Cortical invasion was reported in 23 patients, and medullary invasion was reported in 9 patients. The 5-year LRC and DSS rates were 85 and 88%, respectively. Patients with bone invasion had a significantly higher risk for recurrence than patients without bone invasion. However, the DSS was similar in patients with versus without bone invasion. Patients with a high neutrophil lymphocyte ratio had a higher risk for worse prognosis.
conclusionsThe oncologic outcome in patients undergoing MM for cT1-2 N0 SCC of the lower gingiva was favourable; bone invasion was not uncommon, but it significantly decreased the prognosis in patients undergoing MM.
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