ReviewMedical sciences (Basel, Switzerland)2019
Origins and Impact of Psychological Traits in Polycystic Ovary Syndrome.
Review in Medical sciences (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 19 citations in OpenAlex.
- Weight Changes Are Linked to Adipose Tissue Genes in Overweight Women with Polycystic Ovary Syndrome.International journal of molecular sciences · 2024Trial
- Exploring lifestyle management in polycystic ovary syndrome through implementation frameworks.Experimental physiology · 2026Review
- Elevated circulating adiponectin levels do not prevent anxiety-like behavior in a PCOS-like mouse model.Scientific reports · 2024Article
- Mindfulness acting with awareness and emotional eating among polycystic ovary syndrome women with infertility: the mediating role of depression.Frontiers in psychology · 2024Article
- Enhanced pup retrieval behaviour in a mouse model of polycystic ovary syndrome.Journal of neuroendocrinology · 2022Article
- Anti-Müllerian Hormone and Polycystic Ovary Syndrome in Women and Its Male Equivalent.Biomedicines · 2022Review
- Challenges in diagnosis and understanding of natural history of polycystic ovary syndrome.Clinical endocrinology · 2022Review
- Anxiety and Depression in Women with Polycystic Ovary Syndrome.Medicina (Kaunas, Lithuania) · 2022Article
- Molecular actions of sex hormones in the brain and their potential treatment use in anxiety disorders.Frontiers in psychiatry · 2022Review
- The Complementary and Alternative Medicine for Polycystic Ovary Syndrome: A Review of Clinical Application and Mechanism.Evidence-based complementary and alternative medicine : eCAM · 2021Review
- Animal Models to Understand the Etiology and Pathophysiology of Polycystic Ovary Syndrome.Endocrine reviews · 2020Review
- Transgenerational Inheritance of Reproductive and Metabolic Phenotypes in PCOS Rats.Frontiers in endocrinology · 2020Article
- Naturally Occurring and Experimentally Induced Rhesus Macaque Models for Polycystic Ovary Syndrome: Translational Gateways to Clinical Application.Medical sciences (Basel, Switzerland) · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Women with polycystic ovary syndrome (PCOS) exhibit compromised psychiatric health. Independent of obesity, women with PCOS are more susceptible to have anxiety and depression diagnoses and other neuropsychiatric disorders. During pregnancy women with PCOS display high circulating androgen levels that may cause prenatal androgen exposure affecting the growing fetus and increasing the risk of mood disorders in offspring. Increasing evidence supports a non-genetic, maternal contribution to the development of PCOS and anxiety disorders in the next generation. Prenatal androgenized rodent models reflecting the anxiety-like phenotype of PCOS in the offspring, found evidence for the altered placenta and androgen receptor function in the amygdala, together with changes in the expression of genes associated with emotional regulation and steroid receptors in the amygdala and hippocampus. These findings defined a previously unknown mechanism that may be critical in understanding how maternal androgen excess can increase the risk of developing anxiety disorders in daughters and partly in sons of PCOS mothers. Maternal obesity is another common feature of PCOS causing an unfavorable intrauterine environment which may contribute to psychiatric problems in the offspring. Whether environmental factors such as prenatal androgen exposure and obesity increase the offspring's susceptibility to develop psychiatric ill-health will be discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.