Evidence map›Paper›PMID 31387245›Full record

ArticleInternational journal of molecular sciences2019

Anti-Proliferative and Pro-Apoptotic Effects of Licochalcone A through ROS-Mediated Cell Cycle Arrest and Apoptosis in Human Bladder Cancer Cells.

Su Hyun Hong, Hee-Jae Cha, Hyun Hwang-Bo, Min Yeong Kim, So Young Kim, Seon Yeong Ji, JaeHun Cheong, Cheol Park, Hyesook Lee, Gi-Young Kim and 5 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. The Role of Natural Compounds in Bladder Urothelial Carcinoma Treatment.International journal of molecular sciences · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. A Novel Tri-Hydroxy-Methylated Chalcone Isolated fromInternational journal of molecular sciences · 2023
    Article
  8. Article
  9. Article
  10. Review
  11. Anticancer Potential of Natural Chalcones: In Vitro and In Vivo Evidence.International journal of molecular sciences · 2023
    Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 1 country.

Su Hyun HongAnti-Aging Research Center, Dong-eui University, Busan 47227, Korea.
Hee-Jae ChaDepartment of Parasitology and Genetics, Kosin University College of Medicine, Busan 49267, Korea.ORCID 0000-0002-6963-2685
Hyun Hwang-BoAnti-Aging Research Center, Dong-eui University, Busan 47227, Korea.
Min Yeong KimAnti-Aging Research Center, Dong-eui University, Busan 47227, Korea.
So Young KimAnti-Aging Research Center, Dong-eui University, Busan 47227, Korea.
Seon Yeong JiAnti-Aging Research Center, Dong-eui University, Busan 47227, Korea.
JaeHun CheongDepartment of Molecular Biology, College of Natural Sciences, Pusan National University, Busan 46241, Korea.
Cheol ParkDepartment of Molecular Biology, College of Natural Sciences, Dong-eui University, Busan 47340, Korea.
Hyesook LeeAnti-Aging Research Center, Dong-eui University, Busan 47227, Korea.ORCID 0000-0003-3546-9370
Gi-Young KimDepartment of Marine Life Sciences, School of Marine Biomedical Sciences, Jeju National University, Jeju 63243, Korea.
Sung-Kwon MoonDepartment of Food and Nutrition, Chung-Ang University, Anseong 17546, Korea.
Seok Joong YunDepartment of Urology, College of Medicine, Chungbuk National University, Chungbuk 8644, Korea.
Young-Chae ChangDepartment of Cell Biology, Catholic University of Daegu School of Medicine, Daegu 42472, Korea.
Wun-Jae KimDepartment of Urology, College of Medicine, Chungbuk National University, Chungbuk 8644, Korea. wjkim@chungbuk.ac.kr.
Yung Hyun ChoiAnti-Aging Research Center, Dong-eui University, Busan 47227, Korea. choiyh@deu.ac.kr.ORCID 0000-0002-1454-3124
Dong-Eui University · KRChungbuk National University · KRChung-Ang University · KRDaegu Catholic University · KRJeju National University · KRKosin University · KRPusan National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Licochalcone A (LCA) is a chalcone that is predominantly found in the root of

Indexed as

ApoptosisBiomarkersCaspasesCell Cycle CheckpointsCell Line, TumorCell ProliferationChalconesDose-Response Relationship, DrugHumansMitochondriaReactive Oxygen SpeciesUrinary Bladder NeoplasmsBiomarkersCaspasesChalconeslicochalcone AReactive Oxygen Speciesapoptosisbladder cancerG2/M arrestLicochalcone AROS

Identifiers

PMID31387245
PMCPMC6696302
OpenAlexW2964401309

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.