Evidence map›Paper›PMID 31386852›Full record

ArticleCurrent biology : CB2019

Maternal Inheritance: Longevity Programs Nourish Progeny via Yolk.

Robert H Dowen, Shawn Ahmed

Abstract readComment
PubMed Publisher
In one paragraph

Article in Current biology : CB, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Transgenerational epigenetic inheritance increases trait variation but is not adaptive.Evolution; international journal of organic evolution · 2025
    Article
  2. Article
  3. ADR-2 regulates fertility and oocyte fate inbioRxiv : the preprint server for biology · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Robert H DowenIntegrative Program for Biological and Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address: dowen@email.unc.edu.
Shawn AhmedDepartment of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address: shawn@med.unc.edu.

Funding

Genetic Analysis of Germ Cell ImmortalityR01GM083048 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI AHMED, SHAWN CAMERON · 2007 to 2018
$2.5M
NIGMS NIH HHS R01 GM083048
6 · The paper itself

Abstract

Epigenetic effects can be mediated by changes in chromatin state that are transmitted from parent to child via gametes, but support is gathering for maternal yolk, which is deposited into ooctyes, as an extranuclear epigenetic factor that can contribute to phenotypic plasticity across generations in Caenorhabditis elegans.

Indexed as

LongevityMaternal InheritanceAdaptation, PhysiologicalAnimalsCaenorhabditis elegansChildEpigenesis, GeneticHumansInsulinNutrientsVitellogeninsInsulinNutrientsVitellogenins

Identifiers

PMID31386852

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.