ArticleBJOG : an international journal of obstetrics and gynaecology2019
Association between maternal alcohol consumption during pregnancy and risk of preterm delivery: the Japan Environment and Children's Study.
Article in BJOG : an international journal of obstetrics and gynaecology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Environmental Exposure to Per- and Polyfluorylalkyl Substances (PFASs) and Reproductive Outcomes in the General Population: A Systematic Review of Epidemiological Studies.International journal of environmental research and public health · 2024Pooled it
- Magnitude and risk factors of khat, alcohol and cigarettes use among pregnant women in Africa: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2024Pooled it
- Maternal Diet, Lifestyle Factors, and Gestational Weight Gain: A Single-Center Case-Control Study in Hungary.Nutrients · 2026Article
- Sequelae of preterm birth over the lifespan: an exploratory analysis of behavioral problems in childhood and increased risk of major depression and anxiety in adulthood from a cohort study.EClinicalMedicine · 2025Article
- Gestational Age and Cognitive Development in Childhood.JAMA network open · 2025Article
- Association between antinuclear antibodies status and preterm birth in Japanese pregnant women: a prospective cohort study from Adjunct Study of the Japan Environment and Children's Study.BMC pregnancy and childbirth · 2024Article
- Genetic susceptibility for retinopathy of prematurity and its associated comorbidities.Pediatric research · 2024Article
- Recent Advances and Challenges in the Early Diagnosis and Treatment of Preterm Labor.Bioengineering (Basel, Switzerland) · 2024Review
- Article
- Adverse obstetric outcome and its associated factors in public hospitals of North Ethiopia: does parity make a difference?BMC pregnancy and childbirth · 2022Article
- Healthcare professionals' experiences and perceptions regarding health care of indigenous pregnant women in Ecuador.BMC pregnancy and childbirth · 2022Article
- What Role Does Hispanic/Latina Ethnicity Play in the Relationship Between Maternal Mental Health and Preterm Birth?The Utah women's health review · 2022Article
- Nationwide-free preconception care strategy: Experience from China.Frontiers in public health · 2022Review
- Prevalence and factors associated with preterm birth in a rural district hospital, Rwanda.The Pan African medical journal · 2022Article
- The effects of maternal alcohol consumption during pregnancy on adverse fetal outcomes among pregnant women attending antenatal care at public health facilities in Gondar town, Northwest Ethiopia: a prospective cohort study.Substance abuse treatment, prevention, and policy · 2021Article
- Gestational age and birth growth parameters as early predictors of fetal alcohol spectrum disorders.Alcoholism, clinical and experimental research · 2021Article
- A hierarchical procedure to select intrauterine and extrauterine factors for methodological validation of preterm birth risk estimation.BMC pregnancy and childbirth · 2021Article
- Hypertensive Disorders during Pregnancy (HDP), Maternal Characteristics, and Birth Outcomes among Japanese Women: A Hokkaido Study.International journal of environmental research and public health · 2021Article
- The Role of Innate Immune System in the Human Amniotic Membrane and Human Amniotic Fluid in Protection Against Intra-Amniotic Infections and Inflammation.Frontiers in immunology · 2021Review
- Alcohol-associated liver disease: A review on its pathophysiology, diagnosis and drug therapy.Toxicology reports · 2021Review
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Abstract
objectiveTo examine the association between maternal alcohol consumption during pregnancy and the risk of preterm delivery.
designProspective cohort study.
settingThe Japan Environment and Children's Study (JECS). POPULATION: A total of 94 349 singleton pregnancies.
methodsParticipants completed questionnaires detailing alcohol consumption during the first trimester and during the second and third trimesters. Participants were divided into four categories according to alcohol consumption (non-drinkers, consumers of 1-149 g, 150-299 g and ≥300 g ethanol/week). We examined the effect of alcohol consumption during different stages of pregnancy on the risk of preterm delivery. Odds ratios (OR) and 95% CI were calculated relative to non-drinkers using logistic regression.
main outcome measuresMedical record-based preterm delivery.
resultsAlcohol consumption during the second and third trimesters, but not during the first trimester, was associated with increased risk of preterm delivery. Heavy alcohol consumption (≥300 g ethanol/week) during the second and third trimesters was associated with a four-fold higher risk compared with non-drinkers (multivariable OR 4.52; 95% CI 1.68-12.2). Light alcohol consumption (1-149 g ethanol/week) tended to be associated with lower risk of preterm delivery (multivariable OR 0.78; 95% CI 0.60-1.00).
conclusionsHeavy alcohol consumption during the second and third trimesters was associated with increased risk of preterm delivery among pregnant women. TWEETABLE ABSTRACT: Heavy drinking during pregnancy may increase the risk of preterm delivery.
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