Evidence map›Paper›PMID 31386205›Full record

ArticleAlcoholism, clinical and experimental research2019

Intelligence Test Scores Before and After Alcohol-Related Disorders-A Longitudinal Study of Danish Male Conscripts.

Marie Grønkjaer, Trine Flensborg-Madsen, Merete Osler, Holger Jelling Sørensen, Ulrik Becker, Erik Lykke Mortensen

Open access · hybridAbstract read
In one paragraph

Article in Alcoholism, clinical and experimental research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Marie GrønkjaerFrom the, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-7049-0952
Trine Flensborg-MadsenFrom the, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Merete OslerFrom the, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Holger Jelling SørensenMental Health Centre Copenhagen, Copenhagen University Hospital Gentofte, Gentofte, Denmark.
Ulrik BeckerNational Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.
Erik Lykke MortensenFrom the, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
University of Copenhagen · DKGentofte Hospital · DKUniversity of Southern Denmark · DK

Funding

Det Sundhedsvidenskabelige Fakultet, Københavns UniversitetInnovation Fund Denmark, Health and Clinical Research 603-00520B
6 · The paper itself

Abstract

backgroundExisting studies on intellectual consequences of alcohol-related disorders are primarily cross-sectional and compare intelligence test scores of individuals with and without alcohol-related disorders, hence mixing the influence of alcohol-related disorders and predisposing factors such as premorbid intelligence. In this large-scale study, the primary aim was to estimate associations of alcohol-related disorders with changes in intelligence test scores from early adulthood to late midlife.

methodsData were drawn from a follow-up study on middle-aged men, which included a re-examination of the same intelligence test as completed in young adulthood at military conscription (total analytic sample = 2,499). Alcohol-related hospital diagnoses were obtained from national health registries, whereas treatment for alcohol problems was self-reported at follow-up. The analyses included adjustment for year of birth, retest interval, baseline intelligence quotient (IQ) score, education, smoking, alcohol consumption, and psychiatric and somatic comorbidity.

resultsIndividuals with alcohol-related hospital diagnoses (8%) had a significantly lower baseline IQ score (95.0 vs. 100.5, p < 0.001) and a larger decline in IQ scores from baseline to follow-up (-8.5 vs. -4.8, p < 0.001) than individuals without such diagnoses. The larger decline in IQ scores with alcohol-related hospital diagnoses remained statistically significant after adjustment for all the covariates. Similar results were revealed when IQ scores before and after self-reported treatment for alcohol problems (10%) were examined.

conclusionsIndividuals with alcohol-related disorders have a lower intelligence test score both in young adulthood and in late midlife, and these disorders, moreover, seem to be associated with more age-related decline in intelligence test scores. Thus, low mean intellectual ability observed in individuals with alcohol-related disorders is probably a result of both lower premorbid intelligence and more intellectual decline.

Indexed as

AdultAge of OnsetAlcoholismCross-Sectional StudiesDenmarkFollow-Up StudiesHumansIntelligenceIntelligence TestsLongitudinal StudiesMaleMiddle AgedMilitary PersonnelYoung AdultAlcohol-Related DisordersIntellectual ChangesIntelligenceIntelligence QuotientLongitudinal Study

Identifiers

PMID31386205
PMCPMC6851852
OpenAlexW2965743264

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.