ReviewNeuro-oncology practice2015
Clinical implications of motor deficits related to brain tumors
Review in Neuro-oncology practice, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Physical exercise in brain tumor patients: a systematic review.Frontiers in oncology · 2026Pooled it
- Promoting physical activity in glioma patients: Insights from Dutch healthcare professionals.Neuro-oncology practice · 2026Article
- Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival.Annals of clinical and translational neurology · 2026Article
- Symptom network and latent profile analysis in patients after glioma surgery: a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Mechanical compression induces neuronal apoptosis, reduces synaptic activity, and promotes glial neuroinflammation in mice and humans.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Changes in Somatomotor Network Connectivity Differentiate Better Versus Worse Recovery of Hand Dexterity After Brain Tumor Surgery: A Cohort Study.Neural plasticity · 2026Article
- Impact of Neurorehabilitation on Functional Recovery in patients with Intradural Spinal Cord Tumors: A retrospective analysis in a resource-limited setting.Pakistan journal of medical sciences · 2025Article
- Different Brain Network Connectomic Relationships Subserve Hand Dexterity During Task Versus Resting States in People with Brain Tumors.Brain and behavior · 2025Article
- Leveraging Sarcopenia index by automated CT body composition analysis for pan cancer prognostic stratification.NPJ digital medicine · 2025Article
- Tumor control and motor function in patients with metastases located in the primary motor cortex after stereotactic radiosurgery.Journal of neuro-oncology · 2025Article
- Measures of physical functioning in adults with brain tumor associated with functional outcomes: A scoping review.Neuro-oncology practice · 2025Review
- Brain tumors and fitness to drive: A review and multi-disciplinary approach.Neuro-oncology practice · 2025Review
- [Expert consensus on TZhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025Article
- Evaluating Clinical and Sociodemographic Risk for Symptom Burden Associated Interference With Daily Functioning in the Primary Brain Tumor Patient Population.Cancer medicine · 2025Observational
- Brain tumor patient perceptions toward repetitive transcranial magnetic stimulation for rehabilitation after surgery.Neuro-oncology practice · 2025Article
- The effectiveness of kinesiology taping on dysphagia in brain tumor survivors after neurosurgery: study protocol for a pilot randomized controlled trial.Frontiers in medicine · 2025Article
- Structural changes in eloquent cortex secondary to glioma in sensorimotor area.Human brain mapping · 2024Article
- Perioperative psychological distress in patients with intracranial tumors; a single center study.Journal of neuro-oncology · 2024Article
- Measuring and understanding death anxiety in caregivers of patients with primary brain tumor.Palliative & supportive care · 2023Article
- Relation between Lower Urinary Tract Dysfunction and Functional Outcome in Patients After Brain Tumor Resection.Brain & NeuroRehabilitation · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Motor deficits, including unilateral or bilateral weakness, plegia, ataxia, spasticity, and loss of complex movement execution, can occur during any brain tumor illness. Tumor location, treatment effects, and medications contribute to these deficits. Motor dysfunction has been associated with significant deterioration in health-related quality of life in patients with primary and metastatic brain tumors. Significant decrease in median overall survival has been reported in patients with motor deficits, although the reasons for this are unclear. Motor deficits, particularly gait impairment, contribute to significant symptom burden at end of life, and are the most common reasons for initiation of hospice care. Interventions must focus on prevention and amelioration of motor dysfunction throughout the disease course in order to preserve quality of life. The impact of exercise in prolonging survival and improving quality of life requires further study.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.