Evidence map›Paper›PMID 31386012›Full record

ArticleNeuro-oncology practice2019

Preliminary exploration of a computerized cognitive battery and comparison with traditional testing in patients with high-grade glioma.

Jane H Cerhan, Chip Caine, S Keith Anderson, Derek R Johnson, Daniel H Lachance, Elizabeth Yan, Paul D Brown

Abstract read
In one paragraph

Article in Neuro-oncology practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jane H CerhanDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN.
Chip CaineIntermountain Medical Center, Neurosciences Institute, Intermountain Medical Center, Murray, Utah.
S Keith AndersonDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN.
Derek R JohnsonDepartment of Radiology, Mayo Clinic, Rochester, MN.
Daniel H LachanceDepartment of Neurology, Mayo Clinic, Rochester, MN.
Elizabeth YanDepartment of Radiation Oncology, Mayo Clinic, Rochester, MN.
Paul D BrownDepartment of Radiation Oncology, Mayo Clinic, Rochester, MN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCognitive function is an important outcome measure in many brain tumor clinical trials, and investigators are interested in employing the most efficient methods of cognitive assessment for this purpose. Computerized testing can be appealing because of the perceived ease of use and electronic data generated. Traditional tests may have the advantage of accumulated validity evidence and comparability across historic trials.

methodsWe evaluated feasibility of a Cogstate battery in 39 patients with high-grade glioma, and compared it with a commonly used paper-and-pencil battery.

resultsBoth batteries were well tolerated and rated equally likeable. Correlations between the batteries were low to low-moderate. More patients showed impairment at baseline and decline across trials on traditional tests.

conclusionsBoth batteries were well tolerated, but the most complicated tasks (from both batteries) could not be completed by all subjects. Preliminary validity evidence for the Cogstate tasks was mixed, but a larger sample is needed.

Indexed as

brain tumorclinical trialsCogstateneurocognitiveneuropsychology

Identifiers

PMID31386012
PMCPMC6656319

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.