Evidence map›Paper›PMID 31385987›Full record

ArticleNeuro-oncology practice2017

Palliative and end-of-life care in glioblastoma: defining and measuring opportunities to improve care.

Lauryn E Hemminger, Christine A Pittman, David N Korones, Jennifer N Serventi, Susan Ladwig, Robert G Holloway, Nimish A Mohile

Abstract read
In one paragraph

Article in Neuro-oncology practice, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Palliative care in glioblastoma patients: a systematic review.Revista da Associacao Medica Brasileira (1992) · 2024
    Pooled it
  2. Pooled it
  3. Neuropalliative care in brain cancer.Clinical medicine (London, England) · 2026
    Review
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  15. A retrospective chart review to identify the involvement of palliative care with glioblastoma multiforme patients.Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2023
    Article
  16. Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2023
    Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lauryn E HemmingerUniversity of Rochester School of Medicine (L. E. H); University of Rochester Department of Neurosurgery (C. A. P.); University of Rochester Department of Neurology (J. N. S, R. G. H, N. A.); University of Rochester Department of Pediatrics (D. N. K); University of Rochester Division of Palliative Care (S. L).
Christine A PittmanUniversity of Rochester School of Medicine (L. E. H); University of Rochester Department of Neurosurgery (C. A. P.); University of Rochester Department of Neurology (J. N. S, R. G. H, N. A.); University of Rochester Department of Pediatrics (D. N. K); University of Rochester Division of Palliative Care (S. L).
David N KoronesUniversity of Rochester School of Medicine (L. E. H); University of Rochester Department of Neurosurgery (C. A. P.); University of Rochester Department of Neurology (J. N. S, R. G. H, N. A.); University of Rochester Department of Pediatrics (D. N. K); University of Rochester Division of Palliative Care (S. L).
Jennifer N ServentiUniversity of Rochester School of Medicine (L. E. H); University of Rochester Department of Neurosurgery (C. A. P.); University of Rochester Department of Neurology (J. N. S, R. G. H, N. A.); University of Rochester Department of Pediatrics (D. N. K); University of Rochester Division of Palliative Care (S. L).
Susan LadwigUniversity of Rochester School of Medicine (L. E. H); University of Rochester Department of Neurosurgery (C. A. P.); University of Rochester Department of Neurology (J. N. S, R. G. H, N. A.); University of Rochester Department of Pediatrics (D. N. K); University of Rochester Division of Palliative Care (S. L).
Robert G HollowayUniversity of Rochester School of Medicine (L. E. H); University of Rochester Department of Neurosurgery (C. A. P.); University of Rochester Department of Neurology (J. N. S, R. G. H, N. A.); University of Rochester Department of Pediatrics (D. N. K); University of Rochester Division of Palliative Care (S. L).
Nimish A MohileUniversity of Rochester School of Medicine (L. E. H); University of Rochester Department of Neurosurgery (C. A. P.); University of Rochester Department of Neurology (J. N. S, R. G. H, N. A.); University of Rochester Department of Pediatrics (D. N. K); University of Rochester Division of Palliative Care (S. L).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAmerican Society for Clinical Oncology (ASCO) quality measures for terminal cancers recommend early advance care planning and hospice at the end of life. We sought to evaluate adherence to 5 palliative care quality measures and explore associations with patient outcomes in glioblastoma.

methodsThis is a retrospective analysis of 117 deceased glioblastoma patients over 5 years. Records were reviewed to describe adherence to palliative care quality measures and patient outcomes. Data regarding emotional assessments, advance directives, palliative care consultation, chemotherapy administration, hospice, location of death, and overall survival were collected.

resultsMedian overall survival was 12.9 months. By the second oncology visit, 22.2% (26/117) had an emotional assessment completed. Advance directives were documented for 52.1% (61/117) by the third neuro-oncology visit (30/61 health care proxy), yet 26.5% (31/117) did not have any advance directive before the last month of life. With regard to other ASCO quality measures, 36.8% (43/117) had a palliative care consult; 94.0% (110/117) did not receive chemotherapy in the last 14 days of life; 59.8% (70/117) enrolled in hospice >7 days before death; and 56.4% (66/117) died in a home setting. Patients who enrolled in hospice >7 days before death were 3.56 times more likely to die in a home setting than patients enrolled <7 days before death or with no hospice enrollment (

conclusionsLate advance directive documentation, minimal early palliative care involvement, and the association of early hospice enrollment with death in a home setting underscore the need to improve care and better define palliative care quality measures in glioblastoma.

Indexed as

advance directivesglioblastomahospice carepalliative carequality improvement

Identifiers

PMID31385987
PMCPMC6655415

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.