Evidence map›Paper›PMID 31385960›Full record

ReviewNeuro-oncology practice2018

Brain tumor research in the United Kingdom: current perspective and future challenges. A strategy document from the NCRI Brain Tumor CSG.

Kathreena M Kurian, Michael D Jenkinson, Paul M Brennan, Robin Grant, Sarah Jefferies, Alasdair G Rooney, Helen Bulbeck, Sara C Erridge, Samantha Mills, Catherine McBain and 10 more

Abstract readReview
In one paragraph

Review in Neuro-oncology practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Kathreena M KurianInstitute of Clinical Neurosciences, University of Bristol, Learning and Research Building, Southmead Hospital, Bristol.
Michael D JenkinsonInstitute of Translational Medicine, University of Liverpool.
Paul M BrennanDepartment of Clinical Neurosciences, Western General Hospital, Edinburgh.
Robin GrantDepartment of Clinical Neurosciences, Western General Hospital, Edinburgh.
Sarah JefferiesDepartment of Oncology, Cambridge University Hospitals, Foundation Trust, Cambridge, CB2, UK.
Alasdair G RooneyDivision of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh.
Helen Bulbeckbrainstrust, the brain cancer people, Cowes, UK.
Sara C ErridgeEdinburgh Centre for Neuro-Oncology, Edinburgh Cancer Centre, Western General Hospital, Edinburgh.
Samantha MillsBlizard Institute, Barts and The London Medical School, Queen Mary University of London, London, UK.
Catherine McBainManchester Academic Health Science Centre, University of Manchester, Manchester, UK.
Martin G McCabeDepartment of Clinical Oncology, The Christie NHS Foundation Trust Hospital, Manchester, UK.
Stephen J PriceDepartment of Clinical Neurosciences, Division of Neurosurgery, University of Cambridge, UK.
Silvia MarinoDepartment of Neuroradiology, The Walton Centre NHS Foundation Trust, Liverpool and Informatics, Imaging and Data Sciences, University of Manchester.
Erica MoyesThe Brain Tumor Charity, Farnborough, UK.
Wendy QianCambridge Cancer Trials Centre | Cambridge Clinical Trials Unit-Cancer Theme, Cambridge University Hospitals NHS Foundation Trust.
Adam WaldmanImaging Sciences, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
Babar VaqasDepartment of Surgery, Imperial College Healthcare NHS Trust, Charing Cross Hospital, London.
Debbie KeatleyPatient and Public Involvement Representative.
Peter BurchillPatient and Public Involvement Representative.
Colin WattsDepartment of Clinical Neurosciences, Division of Neurosurgery, University of Cambridge, UK.

Funding

Medical Research Council G0800020Medical Research Council MR/N000528/1
6 · The paper itself

Abstract

The National Cancer Research Institute (NCRI) is a partnership of charity and government research funders whose purpose is to improve health and quality of life by accelerating progress in cancer-related research through collaboration. Under this umbrella, the NCRI Brain Tumor Clinical Studies Group is focused on improving clinical outcomes for adult patients with brain and central nervous system tumors, including those with brain metastasis from other primary sites. This document discusses the current state of clinical brain tumor research in the United Kingdom and the challenges to increasing study and trial opportunities for patients. The clinical research priorities are defined along with a strategy to strengthen the existing brain tumor research network, improve access to tissue and imaging and to develop the future leadership for brain tumor research in the United Kingdom. This strategy document may serve as a framework for other organizations and countries.

Indexed as

brain tumorgliomameningiomaresearch

Identifiers

PMID31385960
PMCPMC6655398

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.