Evidence map›Paper›PMID 31385628›Full record

ArticleMagnetic resonance in medicine2020

Peripheral nerve stimulation limits of a high amplitude and slew rate magnetic field gradient coil for neuroimaging.

Ek T Tan, Yihe Hua, Eric W Fiveland, Mark E Vermilyea, Joseph E Piel, Keith J Park, Vincent B Ho, Thomas K F Foo

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06606925 (Determining Which Regions of the Brain Are Active During Flight Simulation at Separate Timepoints During Training), which is not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06606925 nacompletednot on this mapstarted 2023, after this paper: background citation

Determining Which Regions of the Brain Are Active During Flight Simulation at Separate Timepoints During Training

TypeinterventionalSponsorThe Geneva FoundationRan2023 to 2026Enrolled35ConditionsCognitive PerformanceArmsfMRI with virtual reality flight simulator
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  6. Engineering clinical translation of OGSE diffusion MRI.Magnetic resonance in medicine · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ek T TanGE Research, Niskayuna, New York.ORCID 0000-0003-2847-9378
Yihe HuaGE Research, Niskayuna, New York.
Eric W FivelandGE Research, Niskayuna, New York.
Mark E VermilyeaGE Research, Niskayuna, New York.
Joseph E PielGE Research, Niskayuna, New York.
Keith J ParkGE Research, Niskayuna, New York.
Vincent B HoUniformed Services University of the Health Sciences, Bethesda, Maryland.
Thomas K F FooGE Research, Niskayuna, New York.ORCID 0000-0002-9016-1005
GE Global Research (United States) · USUniformed Services University of the Health Sciences · US

Funding

Lightweight, Compact, Low-Cryogen, Head-Only 7T MRI for High Spatial Resolution Brain ImagingU01EB026976 · NIBIB · GENERAL ELECTRIC GLOBAL RESEARCH CTR · PI FOO, THOMAS K, SHU, YUNHONG · 2018 to 2022
$13.9M
Elimination of Instrumental Bias for Quantitative Diffusion Imaging in Clinical Oncology TrialsR01CA190299 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MALYARENKO, DARIYA I. · 2015 to 2025
$6.4M
High Performance, Highly Deployable Head-Only MRI ScannerR01EB010065 · NIBIB · GENERAL ELECTRIC GLOBAL RESEARCH CTR · PI BERNSTEIN, MATTHEW A., FOO, THOMAS K · 2010 to 2015
$5.5M
High-performance compact 3T MRI: Technical optimization for advanced brain imagingU01EB024450 · NIBIB · MAYO CLINIC ROCHESTER · PI BERNSTEIN, MATTHEW A., FOO, THOMAS K · 2017 to 2021
$5.3M
NCI NIH HHS R01 CA190299NIBIB NIH HHS R01 EB010065NIBIB NIH HHS U01 EB024450NIBIB NIH HHS U01 EB026976
6 · The paper itself

Abstract

purposeTo establish peripheral nerve stimulation (PNS) thresholds for an ultra-high performance magnetic field gradient subsystem (simultaneous 200-mT/m gradient amplitude and 500-T/m/s gradient slew rate; 1 MVA per axis [MAGNUS]) designed for neuroimaging with asymmetric transverse gradients and 42-cm inner diameter, and to determine PNS threshold dependencies on gender, age, patient positioning within the gradient subsystem, and anatomical landmarks.

methodsThe MAGNUS head gradient was installed in a whole-body 3T scanner with a custom 16-rung bird-cage transmit/receive RF coil compatible with phased-array receiver brain coils. Twenty adult subjects (10 male, mean ± SD age = 40.4 ± 11.1 years) underwent the imaging and PNS study. The tests were repeated by displacing subject positions by 2-4 cm in the superior-inferior and anterior-posterior directions.

resultsThe x-axis (left-right) yielded mostly facial stimulation, with mean ΔG

conclusionThe PNS threshold of MAGNUS is significantly higher than that for whole-body gradients, which allows for diffusion gradients with short rise times (under 1 msec), important for interrogating brain microstructure length scales.

Indexed as

Electric StimulationMagnetic FieldsAdultAlgorithmsBrainEquipment DesignFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedNeuroimagingPeripheral NervesPeripheral Nervous SystemPhantoms, Imagingdiffusion imagingelectric fieldhead-only scannermicrostructureMR safetyperipheral nerve stimulation

Identifiers

PMID31385628
PMCPMC6778706
OpenAlexW2965876710

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.