ReviewJournal of biomedical optics2019
Clinical applications of laser speckle contrast imaging: a review.
Review in Journal of biomedical optics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05685862 (Laser Speckle Contrast Imaging, Surgical Eye and Indocyanine Green Fluorescence Imaging for Perfusion Assessment of the Gastric Conduit), which is not on this map. Cited by 130 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Laser Speckle Contrast Imaging, Surgical Eye and Indocyanine Green Fluorescence Imaging for Perfusion Assessment of the Gastric Conduit
Who cites it
130 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Noninvasive hemoglobin sensing and imaging: optical tools for disease diagnosis.Journal of biomedical optics · 2022Pooled it
- Open-Label Interventional Study in Healthy Volunteers to Evaluate NO-Mediated Vasodilation by Dermal Allyl Isothiocyanate Challenge and Whole-Body Heat Stress.Journal of experimental pharmacology · 2024Trial
- Efficient, Capsule-Free Nymphal Ixodid Tick Placement for Site-Specific Attachment to Assess Anti-Tick Host Behavior and Immune Responses.Current protocols · 2026Article
- In Vivo Monitoring of Pressure Ulcer Model Development and Recoverability Under Multimodal Parameters Within a Unified Field of View.Journal of biophotonics · 2026Article
- Optical characterization of a laser speckle contrast imaging system for intraoperative blood flow monitoring.Biomedical optics express · 2026Article
- Rapid noncontact laser speckle imaging for perfusion-based differentiation of wound necrosis.iScience · 2026Article
- Article
- Physics-informed neural network for mapping vascular and tissue dynamics using laser speckle contrast imaging.Neurophotonics · 2026Article
- Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Label-free intraoperative imaging of hemodynamics using deep learning.Biomedical optics express · 2026Article
- Real-time wavelet threshold denoising for laser speckle blood flow imaging.Scientific reports · 2026Article
- Microcirculation Monitoring in Septic Shock: Focused Review.Medicina (Kaunas, Lithuania) · 2026Review
- Septic shock reduces intestinal microcirculation and anastomotic perfusion: A porcine laser speckle contrast imaging study.World journal of gastrointestinal surgery · 2026Article
- Objective evaluation of facial flushing for mesenteric traction syndrome diagnosis during laparotomy: a prospective observational pilot study.JA clinical reports · 2026Article
- Development of a laser speckle contrast imaging analysis pipeline reveals a triphasic retinal blood flow waveform.Biomedical optics express · 2026Article
- Beyond fluorescence intensity: a Minimum acquisition and reporting standard and emerging technologies for colorectal indocyanine green fluorescence angiography studies.Frontiers in surgery · 2026Article
- Effect of the Tracheal Optical Properties on the Spectral Assessment of the Level of Its Blood Supply In Vivo.Diagnostics (Basel, Switzerland) · 2025Article
- Spatial and Temporal Assessment of Cerebral Blood Flow in a Novel Piglet Model of Neonatal Arterial Ischemic Stroke.Translational stroke research · 2025Article
- Semaglutide Mitigates Ischemic Brain Injury by Inhibiting Ferroptosis via Modulation of FoXO1 and DRP1 Pathways.Molecular neurobiology · 2025Article
- Monitoring the changes of spinal artery blood flow (SCBF) and its impact on the safety of spinal cord function during spinal deformity osteotomy by laser speckle imaging: a prospective clinical study.European journal of medical research · 2025Article
70 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
When a biological tissue is illuminated with coherent light, an interference pattern will be formed at the detector, the so-called speckle pattern. Laser speckle contrast imaging (LSCI) is a technique based on the dynamic change in this backscattered light as a result of interaction with red blood cells. It can be used to visualize perfusion in various tissues and, even though this technique has been extensively described in the literature, the actual clinical implementation lags behind. We provide an overview of LSCI as a tool to image tissue perfusion. We present a brief introduction to the theory, review clinical studies from various medical fields, and discuss current limitations impeding clinical acceptance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.