Evidence map›Paper›PMID 31385476›Full record

ArticleThe world journal of men's health2020

Electric Stimulation Hyperthermia Relieves Inflammation

Guan Qun Zhu, Seung Hwan Jeon, Kyu Won Lee, Wen Jie Tian, Hyuk Jin Cho, U Syn Ha, Sung Hoo Hong, Ji Youl Lee, Myeong Keon Moon, Sung Hee Moon and 2 more

Open access · diamondAbstract read
In one paragraph

Article in The world journal of men's health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Guan Qun ZhuDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0001-7841-8026
Seung Hwan JeonDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0001-6695-6097
Kyu Won LeeDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0001-7308-1583
Wen Jie TianDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0002-6037-1319
Hyuk Jin ChoDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0003-2599-2950
U Syn HaDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0001-9930-0588
Sung Hoo HongDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0002-1952-4010
Ji Youl LeeDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0001-6775-1157
Myeong Keon MoonBuheung Medical, Seoul, Korea.ORCID https://orcid.org/0000-0002-4461-371X
Sung Hee MoonBuheung Medical, Seoul, Korea.ORCID https://orcid.org/0000-0002-5310-0131
Sae Woong KimDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0002-9127-9400
Woong Jin BaeDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0001-7703-1161
Catholic University of Korea · KRSeoul Medical Center · KR

Funding

National Research Foundation of Korea 2018M3A9E8020861Seoul St. Mary's Hospital, The Catholic University of Korea
6 · The paper itself

Abstract

purposeChronic prostatitis (CP), including chronic pelvic pain syndrome (CPPS), is the most commonly encountered manifestation of prostatitis. The aim of this study was to evaluate the effect of electric stimulation hyperthermia treatment (ESHT) on CP/CPPS and to explore the underlying mechanism. MATERIALS AND

methodsRWPE-2 cells with lipopolysaccharide-induced inflammation and a prostatitis rat model induced by 17β-estradiol and dihydrotestosterone underwent sham, electric stimulation, or ESHT treatment. Four weeks later, cells, supernatants, and rat prostates were collected for analysis using immunohistochemistry, Western blots, and enzyme-linked immunosorbent assays.

resultsWe found that ESHT improved prostatitis

conclusionsESHT improved CP/CPPS and reversed pathologic changes of prostatitis by inhibiting the SOCS3-TLR4 pathway.

Indexed as

Electric stimulation hyperthermia treatmentNeuroinflammationProstatitisSuppressor of cytokine signaling 3-toll like receptor 4 pathway

Identifiers

PMID31385476
PMCPMC7308236
OpenAlexW2963851967

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.