ReviewBirth defects research2019
Cannabis and the developing brain: What does the evidence say?
Review in Birth defects research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Influence of Cannabis and Nicotine Co-use on Neuromaturation: A Systematic Review of Adolescent and Young Adult Studies.Biological psychiatry · 2021Pooled it
- Telehealth-Plus-mHealth Intervention for Young Adults With Cannabis Use Disorder: Protocol for a Pilot Randomized Controlled Trial.JMIR research protocols · 2026Article
- Does the total consumption model apply to cannabis use?Addiction (Abingdon, England) · 2026Article
- Childhood events as factors in continued cannabis use in adulthood: a longitudinal study of a 30-year follow-up cohort.Journal of cannabis research · 2025Article
- DNA methylation and gene expression of immune cell markers in adolescents with chronic cannabis use: an exploratory study.BMC psychiatry · 2024Article
- A preliminary investigation of physical and mental health features of cannabis & nicotine co-use among adolescents and young adults by sex.Addictive behaviors · 2024Article
- Neurite Orientation Dispersion and Density Imaging (NODDI) of Brain Microstructure in Adolescent Cannabis and Nicotine Use.Behavioral sciences (Basel, Switzerland) · 2024Article
- Cannabis use and neurocognitive performance at 13-14 Years-Old: Optimizing assessment with hair toxicology in the Adolescent brain cognitive development (ABCD) study.Addictive behaviors · 2024Article
- Review
- Nicotine use during late adolescence and young adulthood is associated with changes in hippocampal volume and memory performance.Frontiers in neuroscience · 2024Article
- Adolescents and youths' opinions about the factors associated with cannabis use: a qualitative study based on the I-Change model.BMC nursing · 2023Article
- Prospective, longitudinal study to isolate the impacts of marijuana use on neurocognitive functioning in adolescents.Frontiers in psychiatry · 2023Article
- Cannabinoid Poisoning-Related Emergency Department Visits and Inpatient Hospitalizations in Kentucky, 2017 to 2019.Substance use & misuse · 2023Article
- Associations of cannabis product source and subsequent cannabis use among adolescents.Drug and alcohol dependence · 2022Article
- Reversing the Psychiatric Effects of Neurodevelopmental Cannabinoid Exposure: Exploring Pharmacotherapeutic Interventions for Symptom Improvement.International journal of molecular sciences · 2021Review
- A growing need for youth mental health services in Canada: examining trends in youth mental health from 2011 to 2018.Epidemiology and psychiatric sciences · 2020Article
- Special issue on "Developmental effects of smoking, vaping, and cannabis use".Birth defects research · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Cannabis use during adolescence has been linked to deleterious effects on brain integrity. This article summarizes findings from two prospective investigations (3 and 6 years, on average) on adolescent cannabis use from our laboratory that utilize structural neuroimaging and neurocognitive assessment approaches. Across most studies, findings suggest recency, frequency, and age of onset of cannabis use are likely key variables in predicting poorer neural health outcomes. There is some evidence that preexisting differences in brain architecture may also contribute to vulnerability and outcome differences. Ongoing large-scale prospective studies of youth will be able to disentangle how both cannabis use as well as pre and postexposure differences play a role in divergent outcomes among youth who use cannabis.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.