Evidence map›Paper›PMID 31385451›Full record

ArticleCancer medicine2019

Prolonged postoperative ileus in gastric surgery: Is there any difference between laparoscopic and open surgery?

Wenquan Liang, Jiyang Li, Wang Zhang, Jie Liu, Mingsen Li, Yunhe Gao, Ning Wang, Jianxin Cui, Kecheng Zhang, Hongqing Xi and 2 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in Cancer medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Wenquan LiangDepartment of General Surgery, The First Medical Center of Chinese People's Liberation Army General Hospital, Beijing, People's Republic of China.ORCID 0000-0001-5211-8148
Jiyang LiDepartment of General Surgery, The First Medical Center of Chinese People's Liberation Army General Hospital, Beijing, People's Republic of China.
Wang ZhangDepartment of General Surgery, The First Medical Center of Chinese People's Liberation Army General Hospital, Beijing, People's Republic of China.
Jie LiuDepartment of Vascular and Endovascular Surgery, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Mingsen LiAnorectal Desease Diagnosis and Treatment Center, Tianjin Union Medical Center Nankai University Affiliated Hospital, Tianjin, China.
Yunhe GaoDepartment of General Surgery, The First Medical Center of Chinese People's Liberation Army General Hospital, Beijing, People's Republic of China.
Ning WangDepartment of General Surgery, The First Medical Center of Chinese People's Liberation Army General Hospital, Beijing, People's Republic of China.
Jianxin CuiDepartment of General Surgery, The First Medical Center of Chinese People's Liberation Army General Hospital, Beijing, People's Republic of China.
Kecheng ZhangDepartment of General Surgery, The First Medical Center of Chinese People's Liberation Army General Hospital, Beijing, People's Republic of China.
Hongqing XiDepartment of General Surgery, The First Medical Center of Chinese People's Liberation Army General Hospital, Beijing, People's Republic of China.
Bo WeiDepartment of General Surgery, The First Medical Center of Chinese People's Liberation Army General Hospital, Beijing, People's Republic of China.
Lin ChenDepartment of General Surgery, The First Medical Center of Chinese People's Liberation Army General Hospital, Beijing, People's Republic of China.ORCID 0000-0001-6935-1552
Chinese PLA General Hospital · CNNankai University · CN

Funding

Beijing Municipal Citizen Health Project Z151100003915147Beijing Municipal Citizen Health Project Z171100000417023Beijing Municipal Science and Technology Plan Projects D141100000414002Beijing Municipal Science and Technology Plan Projects Z161100000516237Beijing Nova Program Z181100006218011Chinese PLA General Hospital Big Data Project 2016MBD-012National Key Research and Development Plan 2016YFC0905302National Key Research and Development Plan 2017YFC0908305National Nature Science Foundation of China 81602507National Nature Science Foundation of China 81672319National Nature Science Foundation of China 81773135
6 · The paper itself

Abstract

backgroundProlonged postoperative ileus (PPOI) is a common complication after abdominal surgery, but data about risk factors of PPOI for patients with gastric cancer are rare. We sought to investigate the impact of laparoscopic versus open surgery for PPOI after gastric cancer surgery.

methodsA retrospective cohort study was conducted using a registry database consecutively collected from June 2016 to March 2017. PPOI was defined as no bowel function persisting for more than 4 days. Univariate analysis and multiple logistic regression models were performed to investigate risk factors, and stratified analysis was carried out to examine the primary association at different levels of a potential confounding factor.

resultsA total of 162 patients composed of 63 patients undergoing laparotomy and 99 patients undergoing laparoscopy were enrolled and PPOI was observed in 32 (19.75%) patients. Risk factors significantly correlated with PPOI were as follows: open surgery, older age, late surgical pathologic staging, postoperative use of opioid analgesic, low level of postoperative albumin and serum potassium. Compared to open surgery, the laparoscopic surgery was a strong protective factor for PPOI after adjusting related variables (OR = 0.17, CI: 0.05-0.52, P = .002). There was an interaction between surgical methods and the postoperative WBC level (P for interaction = .007). In the two group stratified analysis of WBC, laparoscopic surgery had a significant lower risk of PPOI than open group for the patients with WBC counts above the middle level in crude or adjusted models. This result remained significantly in the three group stratified analysis for the patients with WBC counts in the middle and or high tertile groups.

conclusionsPPOI is a common postoperative complication of patients after gastrectomy. Laparoscopic surgery is associated with decreased risk of PPOI in gastric surgery. Patients who underwent open surgery and presented with high level of WBC should be cautious with PPOI.

Indexed as

AgedFemaleGastrectomyHumansIleusLaparoscopyLogistic ModelsMalePostoperative ComplicationsPotassiumRetrospective StudiesRisk AssessmentRisk FactorsSerum AlbuminStomach NeoplasmsPotassiumSerum Albumingastric surgerylaparoscopic surgeryopen surgeryparalytic ileusprolonged ileus

Identifiers

PMID31385451
PMCPMC6745839
OpenAlexW2964460050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.