ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2019
Batch and fed-batch production of probiotic biomass and nisin in nutrient-supplemented whey media.
Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Orange Juice as a Substrate for Milk and Water Kefir Grains: Production and Characterization of Novel Kefir-like Beverages.Foods (Basel, Switzerland) · 2026Article
- Valorisation of acid whey permeate for high-purity nisin Z production using artisanal Lactococcus lactis isolates.BMC microbiology · 2025Article
- Lactococcus lactis I7 isolated from traditional Italian cheese making: a biotechnological integrated platform.BMC biotechnology · 2025Article
- Microbiological and Chemical Profiles of Kiwi Kefir-like Beverages Produced Using Different Agitation Speeds and Kefir Grain Weights.Foods (Basel, Switzerland) · 2025Article
- The Role of Whey in Functional Microorganism Growth and Metabolite Generation: A Biotechnological Perspective.Foods (Basel, Switzerland) · 2025Review
- Where Biology Meets Engineering: Scaling Up Microbial Nutraceuticals to Bridge Nutrition, Therapeutics, and Global Impact.Microorganisms · 2025Review
- Improving the survival under gastric conditions of a potential multistrain probiotic produced in co-culture.AMB Express · 2025Article
- Encapsulation improves viability and stability of spray-dried Lactococcus lactis A12 for inclusion in fish feed.PloS one · 2025Article
- Design of an agro-industrial by-products-based media for the production of probiotic bacteria for fish nutrition.Scientific reports · 2024Article
- Automated workflow for characterization of bacteriocin production in natural producers Lactococcus lactis and Latilactobacillus sakei.Microbial cell factories · 2024Article
- Production of a potential multistrain probiotic in co-culture conditions using agro-industrial by-products-based medium for fish nutrition.BMC biotechnology · 2023Article
- Bioactive Ingredients from Dairy-Based Lactic Acid Bacterial Fermentations for Functional Food Production and Their Health Effects.Nutrients · 2023Review
- Novel Probiotic/Bacterial Cellulose Biocatalyst for the Development of Functional Dairy Beverage.Foods (Basel, Switzerland) · 2022Article
- Production of a Potentially Probiotic Product for Animal Feed and Evaluation of Some of Its Probiotic Properties.International journal of molecular sciences · 2021Article
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The production of a highly concentrated probiotic preparation of Lactococcus lactis CECT 539 was studied in both batch and realkalized fed-batch fermentations in diluted whey (DW) media (DW25, DW50, DW75, DW100, and DW125) supplemented with MRS broth nutrients (except glucose and Tween 80) at 25, 50, 75, 100, and 125% of their standard concentrations in the complex medium. The fed-batch culture using DW100 medium provided the highest concentrations of probiotic biomass (5.98 g/L) and nisin (258.47 BU/mL), which were obtained at lower production costs than those estimated for the fed-batch culture in DW medium. The batch and fed-batch cultures reduced the initial chemical oxygen demand (COD) of the media by 29.1-41.7% and 31.2-54.2%, respectively. Graphical abstract.
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