Evidence map›Paper›PMID 31385043›Full record

ReviewWorld journal of microbiology & biotechnology2019

Advances in research on signal molecules regulating biofilms.

Li Yi, Jinpeng Li, Baobao Liu, Yang Wang

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of microbiology & biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Inhibitory Effect of Monoterpenoid Glycosides Extracts from Peony Seed Meal onInternational journal of environmental research and public health · 2022
    Article
  8. Review
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Li YiCollege of Life Science, Luoyang Normal University, Luoyang, China.
Jinpeng LiKey Laboratory of Molecular Pathogen and Immunology of Animal of Luoyang, Luoyang, China.
Baobao LiuKey Laboratory of Molecular Pathogen and Immunology of Animal of Luoyang, Luoyang, China.
Yang WangKey Laboratory of Molecular Pathogen and Immunology of Animal of Luoyang, Luoyang, China. wangyocean@163.com.ORCID http://orcid.org/0000-0002-8266-5262

Funding

National Natural Science Foundation of China 31540095National Natural Science Foundation of China 31772761the National Key Research and Development Program of China 2018YFD0500100
6 · The paper itself

Abstract

Bacterial biofilms (BFs) are membrane-like structures formed by the secretion of extracellular polymeric substances (EPS) by bacteria. The formation of BFs contributes to bacterial survival and drug resistance. When bacteria proliferate, they produce secondary metabolites that act as signaling molecules in bacterial communities that regulate intracellular and cell-to-cell communication. This communication can directly affect the physiological behavior of bacteria, including the production and emission of light (bioluminescence), the expression of virulence factors, the resistance to antibiotics, and the shift between planktonic and biofilm lifestyles. We review the major signaling molecules that regulate BF formation, with a focus on quorum-sensing systems (QS), cyclic diguanylate (c-di-GMP), two-component systems (TCS), and small RNA (sRNA). Understanding these processes will lead to new approaches for treating chronic diseases and preventing bacterial resistance.

Indexed as

Gene Expression Regulation, BacterialSignal TransductionBacteriaBiofilmsCyclic GMPQuorum SensingRNA, BacterialRNA, Small Untranslatedbis(3',5')-cyclic diguanylic acidCyclic GMPRNA, BacterialRNA, Small UntranslatedBiofilmQuorum-sensingSignal moleculeTwo-component systems

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.