ArticleEuropean journal of nuclear medicine and molecular imaging2019
Triple-gated motion and blood pool clearance corrections improve reproducibility of coronary
Article in European journal of nuclear medicine and molecular imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Head-to-head comparison ofJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2024Trial
- Coronary artery disease imaging with total-body PET.The British journal of radiology · 2026Review
- From incidental positron emission uptake toFrontiers in cardiovascular medicine · 2026Review
- Emerging Applications of Positron Emission Tomography in Coronary Artery Disease.Journal of personalized medicine · 2025Review
- Myocardial creep and cardiorespiratory motion correction improves diagnostic accuracy of Rubidium-82 cardiac positron emission tomography.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Latent Coronary Plaque Morphology From Computed Tomography Angiography, Molecular Disease Activity on Positron Emission Tomography, and Clinical Outcomes.Arteriosclerosis, thrombosis, and vascular biology · 2023Article
- The Role of Positron Emission Tomography in Advancing the Understanding of the Pathogenesis of Heart and Vascular Diseases.Diagnostics (Basel, Switzerland) · 2023Review
- Advanced Cardiac Imaging in the Assessment of Aortic Stenosis.Journal of cardiovascular development and disease · 2023Review
- AorticJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Hot spot imaging in cardiovascular diseases: an information statement from SNMMI, ASNC, and EANM.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Advances in the Assessment of Coronary Artery Disease Activity with PET/CT and CTA.Tomography (Ann Arbor, Mich.) · 2023Review
- Anatomical validation of automatic respiratory motion correction for coronary 18F-sodium fluoride positron emission tomography by expert measurements from four-dimensional computed tomography.Medical physics · 2022Article
- Effect of respiratory motion correction and CT-based attenuation correction on dual-gated cardiac PET image quality and quantification.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Non-Invasive Modalities in the Assessment of Vulnerable Coronary Atherosclerotic Plaques.Tomography (Ann Arbor, Mich.) · 2022Review
- Thoracic AorticJACC. Cardiovascular imaging · 2022Observational
- Bypass Grafting and Native Coronary Artery Disease Activity.JACC. Cardiovascular imaging · 2022Article
- Respiration-averaged CT versus standard CT attenuation map for correction ofJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Observer repeatability and interscan reproducibility of 18F-sodium fluoride coronary microcalcification activity.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Aortic valve imaging usingEJNMMI physics · 2022Article
- Machine Learning withJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022Article
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11 authors.
Funding
Abstract
purposeTo improve the test-retest reproducibility of coronary plaque
methodsWe recruited 20 patients with coronary artery disease who underwent repeated hybrid PET/CT angiography (CTA) imaging within 3 weeks. All patients had 30-min PET acquisition and CTA during a single imaging session. Five PET image-sets with progressive motion correction were reconstructed: (i) a static dataset (no-MC), (ii) end-diastolic PET (standard), (iii) cardiac motion corrected (MC), (iv) combined cardiac and gross patient motion corrected (2 × MC) and, (v) cardiorespiratory and gross patient motion corrected (3 × MC). In addition to motion correction, all datasets were corrected for variations in the background activities which are introduced by variations in the injection-to-scan delays (background blood pool clearance correction, BC). Test-retest reproducibility of PET target-to-background ratio (TBR) was assessed by Bland-Altman analysis and coefficient of reproducibility.
resultsA total of 47 unique coronary lesions were identified on CTA. Motion correction in combination with BC improved the PET TBR test-retest reproducibility for all lesions (coefficient of reproducibility: standard = 0.437, no-MC = 0.345 (27% improvement), standard + BC = 0.365 (20% improvement), no-MC + BC = 0.341 (27% improvement), MC + BC = 0.288 (52% improvement), 2 × MC + BC = 0.278 (57% improvement) and 3 × C + BC = 0.254 (72% improvement), all p < 0.001). Importantly, in a sub-analysis of
conclusionJoint corrections for cardiac, respiratory, and gross patient motion in combination with background blood pool corrections markedly improve test-retest reproducibility of coronary
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