Evidence map›Paper›PMID 31384797›Full record

ArticleBMC chemistry2019

Synthesis and evaluation of novel naphthol diazenyl scaffold based Schiff bases as potential antimicrobial and cytotoxic agents against human colorectal carcinoma cell line (HT-29).

Harmeet Kaur, Jasbir Singh, Balasubramanian Narasimhan

Abstract read
In one paragraph

Article in BMC chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Harmeet Kaur1Faculty of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak, 124001 India.
Jasbir Singh2College of Pharmacy, Postgraduate Institute of Medical Sciences, Rohtak, 124001 India.
Balasubramanian Narasimhan1Faculty of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak, 124001 India.ORCID 0000-0002-9627-094X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn search of new antimicrobial and cytotoxic agents, a series of new naphthol diazenyl scaffold based Schiff bases ( METHODOLOGY: The synthesized derivatives were characterized by various physicochemical and spectral techniques and assessed for in vitro antimicrobial and cytotoxic potential against human colorectal carcinoma cell line (HT-29). The active derivatives were further evaluated for their apoptotic potential by Annexin-V/propidium iodide double staining assay using flow cytometer and analyzed for cell-cycle arrest studies. RESULTS AND

conclusionThe derivative

Indexed as

AntimicrobialApoptosisCell cycleDiazenylSchiff base

Identifiers

PMID31384797
PMCPMC6661811

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.