Evidence map›Paper›PMID 31384743›Full record

ArticleVaccine: X2019

Bluetongue virus outer-capsid protein VP2 expressed in

Petra C Fay, Houssam Attoui, Carrie Batten, Fauziah Mohd Jaafar, George P Lomonossoff, Janet M Daly, Peter P C Mertens

Open access · goldAbstract read
In one paragraph

Article in Vaccine: X, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Increased Clinical Signs and Mortality in IFNARPathogens (Basel, Switzerland) · 2023
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Prospects of Next-Generation Vaccines for Bluetongue.Frontiers in veterinary science · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Petra C FayThe Pirbright Institute, Ash Road, Pirbright, Surrey GU24 0NF, UK.
Houssam AttouiUMR VIROLOGIE 1161, INRA, Ecole Nationale Vétérinaire d'Alfort, ANSES, Université Paris-Est, Maisons-Alfort F-94700, France.
Carrie BattenThe Pirbright Institute, Ash Road, Pirbright, Surrey GU24 0NF, UK.
Fauziah Mohd JaafarUMR VIROLOGIE 1161, INRA, Ecole Nationale Vétérinaire d'Alfort, ANSES, Université Paris-Est, Maisons-Alfort F-94700, France.
George P LomonossoffDepartment of Biological Chemistry, John Innes Centre, Norwich NR4 7UH, UK.
Janet M DalySchool of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Leicestershire LE12 5RD, UK.
Peter P C MertensSchool of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Leicestershire LE12 5RD, UK.
The Pirbright Institute · GBÉcole Nationale Vétérinaire d'Alfort · FRJohn Innes Centre · GBUniversity of Nottingham · GB

Funding

Biotechnology and Biological Sciences Research Council BB/D014204/1Biotechnology and Biological Sciences Research Council BBS/E/I/00001446Biotechnology and Biological Sciences Research Council BBS/E/I/00001455Biotechnology and Biological Sciences Research Council BBS/E/J/00000166
6 · The paper itself

Abstract

Bluetongue is a severe, economically important disease of ruminants that is widely distributed in tropical and temperate regions around the world. It is associated with major production losses, restrictions of animal movements and trade, as well as costs associated with developing and implementing effective surveillance and control measures. Mammalian hosts infected with bluetongue virus (BTV) generate a protective neutralising antibody response targeting the major BTV outer-capsid protein and serotype-specific antigen, VP2. BTV VP2 proteins that have been expressed in plants are soluble, with a native conformation displaying neutralising epitopes and can assemble with other BTV structural proteins to form virus-like particles (VLPs). His-tagged VP2 proteins of BTV serotypes 4 and 8 were transiently expressed in

Indexed as

BluetongueBluetongue virusBTVIFNAR −/−Neutralising antibodiesSubunit proteinVaccinationVaccineVP2

Identifiers

PMID31384743
PMCPMC6668234
OpenAlexW2950138390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.