Evidence map›Paper›PMID 31384667›Full record

ArticleMolecular therapy oncolytics2019

Recruitment of Intratumoral CD103

Anna Mistarz, Marcin P Komorowski, Matthew A Graczyk, Margaret Gil, Aimin Jiang, Mateusz Opyrchal, Hanna Rokita, Kunle O Odunsi, Danuta Kozbor

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy oncolytics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Molecular Circuits of Immune Sensing and Response to Oncolytic Virotherapy.International journal of molecular sciences · 2024
    Review
  4. Reprogramming the tumor microenvironment leverages CD8Molecular therapy oncolytics · 2023
    Article
  5. Article
  6. Review
  7. Article
  8. CXCL12 Signaling in the Tumor Microenvironment.Advances in experimental medicine and biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Anna MistarzDepartment of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Marcin P KomorowskiDepartment of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Matthew A GraczykDepartment of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Margaret GilDepartment of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Aimin JiangDepartment of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Mateusz OpyrchalDepartment of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Hanna RokitaFaculty of Biochemistry, Biophysics, and Biotechnology, Jagiellonian University, Kraków, Poland.
Kunle O OdunsiCenter for Immunotherapy, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Danuta KozborDepartment of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Roswell Park Comprehensive Cancer Center · USJagiellonian University · PL

Funding

Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI Dean G. Tang · 1985 to 2026
$116.6M
RPCI-UPCI Ovarian Cancer SPOREP50CA159981 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI MOYSICH, KIRSTEN B., ODUNSI, KUNLE · 2013 to 2025
$19.6M
b-catenin in vaccine-induced anti-tumor CD8 T cell immunityR01CA198105 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI JIANG, AIMIN · 2015 to 2019
$2.0M
The role of CREB3L1 in synergy between oncolytic vaccinia virus and doxorubicinR03CA223623 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI KOZBOR, DANUTA B · 2018 to 2019
$172k
NCI NIH HHS P30 CA016056NCI NIH HHS P50 CA159981NCI NIH HHS R01 CA198105NCI NIH HHS R03 CA223623
6 · The paper itself

Abstract

Intratumoral dendritic cells play an important role in stimulating cytotoxic T cells and driving antitumor immunity. Using a metastatic ovarian tumor model in syngeneic mice, we explored whether therapy with a CXCR4 antagonist-armed oncolytic vaccinia virus activates endogenous CD103

Indexed as

cancer vaccineCXCR4 antagonistdendritic cellsT cellsvirotherapy

Identifiers

PMID31384667
PMCPMC6667789
OpenAlexW2956000446

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.