Evidence map›Paper›PMID 31384455›Full record

ArticleClinical kidney journal2019

Social isolation in chronic kidney disease and the role of mobility limitation.

Ranjani N Moorthi, Kenzie Latham-Mintus

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Clinical kidney journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05560737 (ODYSSEE-vCHAT Mental Health Study), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05560737 unknown statusnot on this mapstarted 2021, after this paper: background citation

ODYSSEE-vCHAT Mental Health Study: A Virtual Community Promoting Health Literacy, Self-Care, and Peer Support for Heart Failure and Kidney Disease

Typeobservational_patient_registrySponsorUniversity Health Network, TorontoRan2021 to 2023Enrolled215ConditionsChronic Heart Failure, Chronic Kidney DiseasesArmsODYSSEE-vCHAT
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Systematic Review of Loneliness and Social Isolation Interventions in Obesity and Obesity-Related Complications.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Pooled it
  2. Article
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  10. Investigating Biological Pathways Underpinning the Longitudinal Association Between Loneliness and Cognitive Impairment.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Article
  11. Article
  12. Nature-Based Interventions for Psychological Wellbeing in Long-Term Conditions: A Systematic Review.International journal of environmental research and public health · 2022
    Review
  13. Article
  14. Article
  15. Characteristics of Academic Adaptation and Subjective Well-Being in University Students with Chronic Diseases.European journal of investigation in health, psychology and education · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Ranjani N MoorthiDepartment of Medicine, Division of Nephrology, Indiana University School of Medicine, Indianapolis, IN, USA.
Kenzie Latham-MintusDepartment of Sociology, Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA.
Indiana University School of MedicineUniversity of Indianapolis · US

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Longitudinal Assessment of Skeletal Muscle Physiology in Dialysis PatientsK23DK102824 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI MOORTHI, RANJANI N. · 2015 to 2019
$892k
NIA NIH HHS U01 AG009740NIDDK NIH HHS K23 DK102824
6 · The paper itself

Abstract

backgroundChronic kidney disease (CKD) is associated with multiple comorbidities, hospitalizations and mortality. In older adults, social isolation and poor mobility contribute to these outcomes. We tested the hypothesis that a glomerular filtration rate (GFR) <45 mL/min/1.73 m

methodsData from 9119 participants, ages 57-107 years, from the 2016 wave of the Health and Retirement Study's Venous Blood Study were used for this cross-sectional analysis. Kidney function measured by estimated GFR (eGFR) was the predictor and patients were classified as CKD Stages 3b-5 or non-CKD Stages 3b-5 (eGFR ≤45 or >45 mL/min/1.73 m

resultsParticipants with CKD Stages 3b-5 (

conclusionCKD Stages 3b-5 was associated with both mobility limitation and social isolation in a population-based study of older adults. In contrast to older adults without CKD Stages 3b-5, mobility limitation did not explain the lack of social contact and poor social participation, suggesting other factors are more important.

Indexed as

CKDelderlymobilityoutcomessocial isolation

Identifiers

PMID31384455
PMCPMC6671555
OpenAlexW2908535232

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.