Evidence map›Paper›PMID 31384443›Full record

ArticleClinical kidney journal2019

Acute kidney injury among paediatric emergency room admissions in a tertiary hospital in South West Nigeria: a cohort study.

Adebowale D Ademola, Adanze O Asinobi, Esther Ekpe-Adewuyi, Adejumoke I Ayede, Samuel O Ajayi, Yemi R Raji, Babatunde L Salako, Matthew James, Michael Zappitelli, Susan M Samuel

Abstract read
In one paragraph

Article in Clinical kidney journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Paediatric Nephrology in Africa.Current pediatrics reports · 2021
    Review
  10. Review
  11. Observational
  12. Article
  13. Challenges and Outcomes of Paediatric Dialysis in a Tertiary Referral Hospital, Northwest Nigeria.Nigerian medical journal : journal of the Nigeria Medical Association
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Adebowale D AdemolaDepartment of Pediatrics, Faculty of Clinical Sciences, College of Medicine, University of Ibadan, Oyo State, Nigeria.ORCID 0000-0001-9465-2744
Adanze O AsinobiDepartment of Pediatrics, Faculty of Clinical Sciences, College of Medicine, University of Ibadan, Oyo State, Nigeria.
Esther Ekpe-AdewuyiDivision of Nephrology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Adejumoke I AyedeDepartment of Pediatrics, Faculty of Clinical Sciences, College of Medicine, University of Ibadan, Oyo State, Nigeria.
Samuel O AjayiDepartment of Medicine, Faculty of Clinical Sciences, College of Medicine, University of Ibadan, Oyo State, Nigeria.
Yemi R RajiDepartment of Medicine, Faculty of Clinical Sciences, College of Medicine, University of Ibadan, Oyo State, Nigeria.
Babatunde L SalakoDepartment of Medicine, Faculty of Clinical Sciences, College of Medicine, University of Ibadan, Oyo State, Nigeria.
Matthew JamesDivision of Nephrology, Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Michael ZappitelliDivision of Nephrology, Department of Pediatrics, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Susan M SamuelSection of Nephrology, Department of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEpidemiological data on paediatric acute kidney injury (AKI) in sub-Saharan Africa are limited and largely retrospective. We performed a prospective study of AKI among patients admitted through the emergency room.

methodsChildren admitted to the post-neonatal emergency room of the University College Hospital, Ibadan, Nigeria between February 2016 and January 2017 were studied. AKI was defined by Kidney Disease: Improving Global Outcomes serum creatinine criteria. AKI ascertainment relied on serum creatinine measurements carried out in routine care by post-admission Day 1. We compared in-hospital mortality by post-admission Day 7 for patients with and without AKI (no-AKI).

resultsOf the 1344 children admitted to the emergency room, 331 were included in the study. AKI occurred in 112 patients (33.8%) with a median age of 3.1 years [interquartile range (IQR) 0.9-9.4] and was Stage 3 in 50.5% of the cases. The no-AKI group had a median age of 1.8 (IQR 0.7-5.8) years. The underlying diagnoses in patients with AKI were sepsis (33.0%), malaria (12.5%) and primary renal disorders (13.4%). Twenty-four of the patients with AKI underwent dialysis: haemodialysis in 20 and peritoneal dialysis in 4. By Day 7 of admission, 7 of 98 (7.1%) patients in the AKI group had died compared with 5 of 175 (2.9%) patients in the no-AKI group [odds ratio 2.6 (95% confidence interval 0.8-8.5)]. Outcome data were not available for 58 (17.5%) patients.

conclusionsAKI is common among paediatric emergency room admissions in a tertiary care hospital in sub-Saharan Africa. It is associated with high mortality risk that may be worse in settings without dialysis.

Indexed as

acute kidney injurychildrendialysismortalitysub-Saharan Africa

Identifiers

PMID31384443
PMCPMC6671520

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.