ArticleClinical kidney journal2019
Chronic exposure to cadmium is associated with a marked reduction in glomerular filtration rate.
Article in Clinical kidney journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- The preventive and carcinogenic effect of metals on cancer: a systematic review.BMC public health · 2024Pooled it
- Breastmilk cadmium levels and estimated infant exposure: a multicenter study of associated factors in a resource-limited country.International breastfeeding journal · 2023Article
- Application of probabilistic methods to address variability and uncertainty in estimating risks for non-cancer health effects.Environmental health : a global access science source · 2023Article
- Dose-Response Analysis of the Tubular and Glomerular Effects of Chronic Exposure to Environmental Cadmium.International journal of environmental research and public health · 2022Article
- Analysis of Threshold Effect of Urinary Heavy Metal Elements on the High Prevalence of Nephrolithiasis in Men.Biological trace element research · 2022Article
- Effects of Environmental Exposure to Cadmium and Lead on the Risks of Diabetes and Kidney Dysfunction.International journal of environmental research and public health · 2022Article
- Association between Enzyme-Linked Immunosorbent Assay-Measured Kidney Injury Markers and Urinary Cadmium Levels in Chronic Kidney Disease.Journal of clinical medicine · 2021Article
- Plasma Vitamin BNutrients · 2021Article
- The Effect of Cadmium on GFR Is Clarified by Normalization of Excretion Rates to Creatinine Clearance.International journal of molecular sciences · 2021Article
- Plasma and urinary concentrations of arachidonic acid-derived eicosanoids are associated with diabetic kidney disease.EXCLI journal · 2021Article
- Effects of Cadmium, Lead, and Mercury on the Structure and Function of Reproductive Organs.Toxics · 2020Review
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Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUrinary 20-hydroxyeicosatetraenoic acid (20-HETE) has been associated with hypertension in women with elevated urinary cadmium (Cd) excretion rates. The present study investigates the urinary Cd and 20-HETE levels in relation to the estimated glomerular filtration rate (eGFR) and albumin excretion in men and women.
methodsA population-based, cross-sectional study, which included 225 women and 84 men aged 33-55 years, was conducted in a rural area known to be polluted with Cd.
resultsIn all subjects, lower eGFR values were associated with higher urinary Cd excretion (P = 0.030), and tubulopathy markers
conclusionsTubulopathy is a determinant of albumin excretion in women, while 20-HETE and SBP are determinants of urinary albumin excretion in men. Associations of chronic exposure to Cd with marked eGFR decline and renal tubular injury seen in both Cd-exposed men and women add to mounting research data that links Cd to the risk of developing chronic kidney disease.
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