Evidence map›Paper›PMID 31384390›Full record

ArticleOncotarget2019

Oncologist uptake of comprehensive genomic profile guided targeted therapy.

Mary K Nesline, Paul DePietro, Grace K Dy, Amy Early, Antonios Papanicolau-Sengos, Jeffrey M Conroy, Felicia L Lenzo, Sean T Glenn, Hongbin Chen, Anne Grand'Maison and 12 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 2 institutions in 1 country.

Mary K NeslineOmniSeq Inc., Buffalo, NY 14203, USA.
Paul DePietroOmniSeq Inc., Buffalo, NY 14203, USA.
Grace K DyDepartment of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Amy EarlyDepartment of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Antonios Papanicolau-SengosOmniSeq Inc., Buffalo, NY 14203, USA.
Jeffrey M ConroyOmniSeq Inc., Buffalo, NY 14203, USA.
Felicia L LenzoOmniSeq Inc., Buffalo, NY 14203, USA.
Sean T GlennOmniSeq Inc., Buffalo, NY 14203, USA.
Hongbin ChenDepartment of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Anne Grand'MaisonDepartment of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Patrick BolandDepartment of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Marc S ErnstoffDepartment of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Igor PuzanovDepartment of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Stephen EdgeDepartment of Surgery, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Stacey AkersDepartment of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Mateusz OpyrchalDepartment of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Gurkamal ChattaDepartment of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Kunle OdunsiDepartment of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Peter FrederickDivision of Gynecologic Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Shashikant LeleDivision of Gynecologic Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Mark GardnerOmniSeq Inc., Buffalo, NY 14203, USA.
Carl MorrisonOmniSeq Inc., Buffalo, NY 14203, USA.
Roswell Park Comprehensive Cancer Center · USCancer Genetics (United States) · US

Funding

Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI MARK G FRATTINI · 1985 to 2026
$116.6M
Network Lead Academic Participating Site Grant from the Roswell Park Cancer InstituteUG1CA233191 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI LELE, SHASHIKANT, LEVINE, ELLIS G · 2019 to 2025
$3.1M
NCI NIH HHS P30 CA016056NCI NIH HHS UG1 CA233191
6 · The paper itself

Abstract

We describe the extent to which comprehensive genomic profiling (CGP) results were used by oncologists to guide targeted therapy selection in a cohort of solid tumor patients tested as part of standard care at Roswell Park Comprehensive Cancer Center June 2016-June 2017, with adequate follow up through September 2018 (

Indexed as

clinical decision makingcomprehensive genomic profilingnext-generation sequencingreal world datatargeted therapy

Identifiers

PMID31384390
PMCPMC6659802
OpenAlexW2981540121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.