ArticleThe Pan African medical journal2019
Depression and medication-adherence in patients with hypertension attending a tertiary health facility in South-West Nigeria.
Article in The Pan African medical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 4 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- High Burden and Trend in Nonadherence to Blood Pressure-Lowering Medications: Meta-Analysis of Data From Over 34 000 Adults With Hypertension in Sub-Saharan Africa.Journal of the American Heart Association · 2025Pooled it
- Adherence to antihypertensives in the United States: A comparative meta-analysis of 23 million patients.Journal of clinical hypertension (Greenwich, Conn.) · 2024Pooled it
- Prevalence and determinants of medication adherence among patients taking antihypertensive medications in Africa: A systematic review and meta-analysis 2010-2021.Nursing open · 2023Pooled it
- Epidemiology of depressive disorders in people living with hypertension in Africa: a systematic review and meta-analysis.BMJ open · 2020Pooled it
- Article
- A cross-sectional study of the influence of patient experience and psychological contract on medication adherence in depressive patients.Exploratory research in clinical and social pharmacy · 2026Article
- Construction of a machine learning-based risk prediction model for depression in middle-aged and elderly hypertensive people in China: a longitudinal study.Frontiers in psychiatry · 2024Article
- Measurement Tools and Utility of Hair Analysis for Screening Adherence to Antihypertensive Medication.Global heart · 2023Review
- Determination of level of self-reported adherence of antihypertensive drug(s) and its associated factors among patient with hypertension at a tertiary care center.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- Associations Between Personality Functioning, Childhood Trauma and Non-adherence in Cardiovascular Disease: A Psychodynamically-Informed Cross-Sectional Study.Frontiers in psychology · 2022Article
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3 authors.
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Abstract
introductionIn Nigeria, approximately 4.33 million adults suffer from hypertension and about a third of them do not adhere to prescribed medications. Depression has been reported to significantly predict poor medication adherence. The relationship between medication non-adherence and co-morbid depressive disorder in patients with hypertension has not been adequately explored in this environment. The study aimed to determine the prevalence of depression in patients with hypertension. The association between socio-demographic characteristics and presence of co-morbidity on medication adherence was also determined.
methodsA cross-sectional descriptive research design was adopted for the study. A socio-demographic questionnaire, the modified Morisky Medication Adherence Scale (MMAS), the Hamilton Rating Scale for Depression (HAM-D) and the Mini International Neuropsychiatric Interview (MINI), were administered to four hundred patients with hypertension attending medical out-patient clinic between August and September 2012.
resultsAbout 43% (168) were aged 61 to 64 years the majority being females, with a female to male ratio of 1.63:1. The prevalence of comorbid depression was 22.8%, made up of mild (21.8%) and moderate (1.0%) depressive episodes only. Depression was commoner among females than males in a ratio of 3:1. A majority of the participants (96.8%) had high medication adherence; 2.8% and 0.4% had moderate and low adherence respectively. Depression was more among patients with good medication adherence.
conclusionThe occurrence of mild depressive disorder among hypertensives did not affect the level of medication adherence. Review of Antihypertensive drugs should also be done often to ensure patients are not likely to have depressive illness as a side effect of drugs used.
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