Evidence map›Paper›PMID 31384324›Full record

ReviewExperimental and therapeutic medicine2019

Capsaicin: Physicochemical properties, cutaneous reactions and potential applications in painful and inflammatory conditions.

Mihaela Adriana Ilie, Constantin Caruntu, Mircea Tampa, Simona-Roxana Georgescu, Clara Matei, Carolina Negrei, Rodica-Mariana Ion, Carolina Constantin, Monica Neagu, Daniel Boda

Open access · diamondAbstract readReview
In one paragraph

Review in Experimental and therapeutic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it, 88 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Capsaicin: Emerging Pharmacological and Therapeutic Insights.Current issues in molecular biology · 2024
    Review
  9. Galacturonic acid-capsaicin prodrug for prolonged nociceptive-selective nerve blockade.Journal of controlled release : official journal of the Controlled Release Society · 2024
    Article
  10. Review
  11. Pills of Multi-Target HInternational journal of molecular sciences · 2024
    Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Anticancer Activity of Region B Capsaicin Analogs.Journal of medicinal chemistry · 2023
    Review
  18. Article
  19. Mechanisms of Transmission and Processing of Pain: A Narrative Review.International journal of environmental research and public health · 2023
    Review
  20. Chronic Nodular Prurigo: An Update on the Pathogenesis and Treatment.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Mihaela Adriana IlieDermatology Research Laboratory, 'Carol Davila' University of Medicine and Pharmacy, Bucharest 020021, Romania.
Constantin CaruntuDepartment of Physiology, 'Carol Davila' University of Medicine and Pharmacy, Bucharest 020021, Romania.
Mircea TampaDepartment of Dermatology, 'Carol Davila' University of Medicine and Pharmacy, Bucharest 020021, Romania.
Simona-Roxana GeorgescuDepartment of Dermatology, 'Carol Davila' University of Medicine and Pharmacy, Bucharest 020021, Romania.
Clara MateiDepartment of Dermatology, 'Carol Davila' University of Medicine and Pharmacy, Bucharest 020021, Romania.
Carolina NegreiDepartment of Toxicology, Faculty of Pharmacy, 'Carol Davila' University of Medicine and Pharmacy, Bucharest 020956, Romania.
Rodica-Mariana IonThe National Institute for Research and Development in Chemistry and Petrochemistry - ICECHIM, Bucharest 060021, Romania.
Carolina ConstantinDepartment of Immunology, 'Victor Babes' National Institute of Pathology, Bucharest 050096, Romania.
Monica NeaguDepartment of Immunology, 'Victor Babes' National Institute of Pathology, Bucharest 050096, Romania.
Daniel BodaDermatology Research Laboratory, 'Carol Davila' University of Medicine and Pharmacy, Bucharest 020021, Romania.
Carol Davila University of Medicine and Pharmacy · ROInstitutul National Victor Babes · ROInstitutul Naţional de Cercetare Dezvoltare pentru Chimie si Petrochimie · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Capsaicin is a natural protoalkaloid recognized as the main pungent component in hot peppers (

Indexed as

capsaicindesensitizationhyperalgesianeurotoxicityskin reactions

Identifiers

PMID31384324
PMCPMC6639979
OpenAlexW2937739139

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.