Evidence map›Paper›PMID 31384306›Full record

ArticleTherapeutic advances in gastroenterology2019

Vitamin D metabolites are lower with active Crohn's disease and spontaneously recover with development of remission.

Craig Haifer, Ian C Lawrance, Jacqueline R Center, Michael W Clarke, Prue H Hart, John A Eisman, Robyn Lucas, Simon Ghaly

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Therapeutic advances in gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Assessing vitamin D as a biomarker in inflammatory bowel disease.JGH open : an open access journal of gastroenterology and hepatology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Craig HaiferDepartment of Gastroenterology, St Vincent's Hospital, 390 Victoria St, Darlinghurst, NSW 2010, Australia.ORCID https://orcid.org/0000-0002-3675-6550
Ian C LawranceSt John of God Hospital, Centre for Inflammatory Bowel Disease, Subiaco, Australia.
Jacqueline R CenterThe Garvan Institute of Medical Research, Osteoporosis and Bone Biology Division, Sydney, Australia.
Michael W ClarkeThe University of Western Australia, Centre for Microscopy, Characterization and Analysis, Perth, Australia.
Prue H HartTelethon Kids Institute, Inflammation, Subiaco, Australia.
John A EismanThe Garvan Institute of Medical Research, Osteoporosis and Bone Biology Division, Sydney, Australia.
Robyn LucasNational Centre for Epidemiology and Population Health, Research School of Population Health, The Australian National University, Canberra, Australia.
Simon GhalySt Vincent's Hospital, Department of Gastroenterology, Sydney, Australia.
Australian National University · AUGarvan Institute of Medical Research · AUSt John of God Subiaco Hospital · AUSt Vincent's Hospital Sydney · AUThe Kids Research Institute Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVitamin D deficiency is associated with active Crohn's disease (CD). However, it remains unclear if lower 25-hydroxyvitamin D [25(OH)D] concentration is the cause, or consequence, of intestinal inflammation. Existing literature has focused on circulating 25(OH)D rather than the active metabolite 1,25(OH)

methodsFifty-four patients with CD and not on corticosteroids or vitamin D supplements, were enrolled in a 6-month prospective cohort study. Sera were collected on enrolment and at 6 months and tested for 25(OH)D, 1,25(OH)

resultsThere were no differences in 25(OH)D or 1,25(OH)

conclusionLevels of 24,25(OH)

Indexed as

Crohn’s diseaseinflammatory bowel diseasevitamin D

Identifiers

PMID31384306
PMCPMC6661794
OpenAlexW2966605023

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.