ReviewThe International journal of angiology : official publication of the International College of Angiology, Inc2019
The Impella Device: Historical Background, Clinical Applications and Future Directions.
Review in The International journal of angiology : official publication of the International College of Angiology, Inc, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 1 synthesis or guideline pooled it, 127 citations in OpenAlex.
- Impella Versus VA-ECMO in Cardiogenic Shock: An Updated Systematic Review and Meta-Analysis With Exploratory Matched-Cohort Analyses.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026Pooled it
- UK multisociety consensus statement on the emergency management and resuscitation of patients with left-sided Impella support.Heart (British Cardiac Society) · 2026Article
- Four-Dimensional Cine Cinematic Rendering of Structural Heart and Mechanical Circulatory Support Devices: An Illustrative Technical Experience.Journal of imaging · 2026Article
- Axial Flow Percutaneous Ventricular Assist Devices: Physiology, Procedural Considerations, and Clinical Applications-A State-of-the-Art Review.Structural heart : the journal of the Heart Team · 2026Review
- Cardiogenic Shock: Clinical Management, Outcomes and Future Directions.Journal of cardiovascular development and disease · 2026Review
- Coronary Artery Bypass Surgery in a Patient With an Occluded Abdominal Aorta Supported by Microaxial Left Ventricular Assist Device.Annals of thoracic surgery short reports · 2026Article
- Successful treatment ofEuropean heart journal. Case reports · 2026Article
- Short-Term Percutaneous Mechanical Circulatory Support in Acute Coronary Syndrome with Cardiogenic Shock: Which Device to Choose?Journal of cardiovascular development and disease · 2026Review
- Impact of the United Network for Organ Sharing allocation criteria changes on temporary mechanical circulatory support use as a bridge to transplant.World journal of transplantation · 2025Review
- Thyroid storm-induced cardiovascular complications and modalities of therapy: Up-to-date review.World journal of critical care medicine · 2025Review
- Coronary Intervention: History and Current Status.The International journal of angiology : official publication of the International College of Angiology, Inc · 2025Review
- Cardiovascular Physiology During Mechanical Circulatory Support: Implications for Management and Monitoring.Journal of clinical medicine · 2025Review
- The Role of Impella in Cardiogenic Shock in the Post-DanGer Shock Era.Biomedicines · 2025Review
- Navigating high-risk PCI with axillary impella support: a case report.Annals of medicine and surgery (2012) · 2025Article
- Tissue Plasminogen Activator to Resolve Elevated Purge System Pressure in a Catheter-Based Ventricular Assist Device.JACC. Case reports · 2025Article
- Advances in Mechanical Circulatory Support (MCS): Literature Review.Biomedicines · 2025Review
- Variations in the Medical Device Authorization and Reimbursement Landscape: A Case Study of 2 Cardiovascular Devices Across 4 Countries.Circulation. Cardiovascular quality and outcomes · 2025Article
- Short- and long-term outcomes of Impella-protected, high-risk, elective PCI in patients with multivessel coronary disease and low ejection fraction - Polish Impella Registry.Cardiology journal · 2025Article
- Temporary Mechanical Circulatory Support for Acute Myocardial Infarction Cardiogenic Shock.Methodist DeBakey cardiovascular journal · 2025Review
- Role of computed tomography and chest radiography in imaging of Impella heart pump and associated complications.Journal of clinical imaging science · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Impella device is a catheter-based miniaturized ventricular assist device. Using a retrograde femoral artery access, it is placed in the left ventricle across the aortic valve. The device pumps blood from left ventricle into ascending aorta and helps to maintain a systemic circulation at an upper rate between 2.5 and 5.0 L/min. This results in almost immediate and sustained unloading of the left ventricle, while increasing overall systemic cardiac output. The most common indications for using the Impella device are in the treatment of acute myocardial infarction complicated by cardiogenic shock and to facilitate high risk coronary angioplasty. Other indications include the treatment of cardiomyopathy with acute decompensation, postcardiotomy shock, and off-pump coronary bypass surgery. A growing body of observational and registry data suggest a potentially valuable role for the Impella system in reducing the mortality associated with cardiogenic shock. However, there are, as of yet, no randomized controlled trial data supporting this observation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.