Evidence map›Paper›PMID 31383978›Full record

Trial reportEuropean journal of clinical nutrition2020

Effects of LC-PUFA supply via complementary food on infant development-a food based intervention (RCT) embedded in a total diet concept.

Hermann Kalhoff, Christina M Mesch, Madlen Stimming, Andreas Israel, Christoph Spitzer, Latifa Beganovic, Rocio Estella Perez, Berthold Koletzko, Petra Warschburger, Mathilde Kersting and 1 more

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of clinical nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hermann Kalhoff *Pediatric Clinic Dortmund, Dortmund, Germany. hermann.kalhoff@klinikumdo.de.
Christina M Mesch *Research Department of Child Nutrition (FKE), Pediatric University Clinic, Ruhr University, Bochum, Germany.
Madlen StimmingResearch Department of Child Nutrition (FKE), Pediatric University Clinic, Ruhr University, Bochum, Germany.
Andreas IsraelNeurological Clinic, Lüdenscheid, Germany.
Christoph SpitzerKlinikum Arnsberg, Arnsberg, Germany.
Latifa BeganovicPediatric Clinic Dortmund, Dortmund, Germany.
Rocio Estella PerezPediatric Clinic Dortmund, Dortmund, Germany.
Berthold KoletzkoLMU-Ludwig-Maximilians-Universität Munich, Dr. von Hauner Children's Hospital, University of Munich Medical Centre, Munich, Germany.
Petra WarschburgerDepartment Psychology, Potsdam University, Potsdam, Germany.
Mathilde Kersting *Research Department of Child Nutrition (FKE), Pediatric University Clinic, Ruhr University, Bochum, Germany.
Lars Libuda *Research Department of Child Nutrition (FKE), Pediatric University Clinic, Ruhr University, Bochum, Germany.

Funding

Bundesministerium für Bildung und Forschung (Federal Ministry of Education and Research) 01EA1335ABundesministerium für Bildung, Wissenschaft, Forschung und Technologie (Federal Ministry for Education, Science, Research and Technology) 01EA1335A
6 · The paper itself

Abstract

backgroundWith the introduction of complementary food, long-chain PUFA (LC-PUFA) supply usually decreases during the second 6 months of life. However, the need for LC-PUFA is still high for infant's rapid development. The aim of this randomized, controlled intervention trial was to examine the effects of an increased n-3 (LC-)PUFA supply using alternative complementary foods on infants' visual and cognitive development.

methodsMother-child dyads of term infants were recruited in maternity hospitals and randomly assigned to one of three study groups, which all were fed according to the German dietary schedule for infant nutrition. Intervention group IG-R (n = 54) received jars of complementary food with rapeseed oil, IG-F (n = 48) jars with oily fish twice a week and the control group (CG, n = 58) the same jars as IG-R with corn oil instead of rapeseed oil during the intervention period (5th-10th month of age). The outcome measures were latencies of FVEP, Bayley's mental developmental index (MDI), and psychomotor developmental index (PDI).

resultsAt 10 months of age, there were no significant differences in latencies of FVEP, Bayley's MDI, or in PDI index between the intervention and control groups.

conclusionsFish and rapeseed oil used as (LC-)PUFA sources provided with complementary feeding embedded in a structured infant diet did not affect visual or cognitive development of term infants.

Indexed as

Child DevelopmentDietFatty Acids, UnsaturatedInfant FoodInfant Nutritional Physiological PhenomenaAdultAnimalsCorn OilFemaleFishesHumansInfantMothersPregnancyRapeseed OilCorn OilFatty Acids, UnsaturatedRapeseed Oil

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.