Evidence map›Paper›PMID 31383946›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2019

Treating infants with neonatal abstinence syndrome: an examination of three protocols.

Morgan J Hartgrove, Laurie L Meschke, Terry L King, Carla Saunders

Abstract read
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In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Predictors of pharmacologic therapy for neonatal opioid withdrawal syndrome: a retrospective analysis of a statewide database.Journal of perinatology : official journal of the California Perinatal Association · 2021
    Article
  2. Article
  3. Adverse neonatal outcomes associated with maternal severe mental health diagnoses and opioid use.Journal of perinatology : official journal of the California Perinatal Association · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Morgan J HartgroveUniversity of Tennessee, Knoxville, TN, 37996, USA.
Laurie L MeschkeDepartment of Public Health, University of Tennessee, Knoxville, TN, 37996, USA. LLMeschke@utk.edu.ORCID http://orcid.org/0000-0002-9019-9927
Terry L KingClinical Pharmacy, East Tennessee Children's Hospital, Knoxville, TN, 37916, USA.
Carla SaundersPediatrix Medical Group & East TN Children's Hospital, Knoxville, TN, 37916, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDescribe the characteristics of infants with NAS and determine if treatment outcomes varied between three protocols. STUDY

designBased on medical record data, infant treatment for NAS-related withdrawal reflected one of three protocols: (1) No rescue dose (n = 836, 52.7%): Prescriber ordered initiation and escalation doses and determined when infants were eligible for weaning, (2) Rescue dose (n = 233, 14.7%): No rescue dose with the addition of a prescriber-ordered rescue dose, (3) Rescue dose by order set (n = 516, 32.6%): Rescue dose with addition of nurse-assisted order of morphine during escalation.

resultsThe no rescue dose group had longer length of stay, days to wean, and inpatient days, and greater initial morphine dose than the two rescue dose groups (p < 0.001). Treatment outcomes between the two rescue dose protocols did not differ.

conclusionsThe benefits related to rescue dosing further inform the development of a standardized NAS treatment protocol.

Indexed as

Clinical ProtocolsAnalgesics, OpioidAnalysis of VarianceBirth WeightDrug Administration ScheduleGestational AgeHumansInfant, NewbornInfant, PrematureInfant, Premature, DiseasesLength of StayMorphineNarcoticsNeonatal Abstinence SyndromeOpioid-Related DisordersRetrospective StudiesAnalgesics, OpioidMorphineNarcotics

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.