Evidence map›Paper›PMID 31383913›Full record

ArticleScientific reports2019

Structure functional insights into calcium binding during the activation of coagulation factor XIII A.

Sneha Singh, Johannes Dodt, Peter Volkers, Emma Hethershaw, Helen Philippou, Vytautus Ivaskevicius, Diana Imhof, Johannes Oldenburg, Arijit Biswas

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Article
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  3. Preparative leukapheresis impairs autologous donor hemostasis and platelet function.Research and practice in thrombosis and haemostasis · 2026
    Observational
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sneha SinghInstitute of Experimental Hematology and Transfusion medicine, University Hospital of Bonn, Bonn, 53127, Germany.
Johannes DodtPaul-Ehrlich Institute, Langen, 63225, Germany.ORCID http://orcid.org/0000-0002-1078-8298
Peter VolkersPaul-Ehrlich Institute, Langen, 63225, Germany.
Emma HethershawDiscovery and Translational Science Department, University of Leeds, Leeds, LS29JT, United Kingdom.ORCID http://orcid.org/0000-0002-4366-278X
Helen PhilippouDiscovery and Translational Science Department, University of Leeds, Leeds, LS29JT, United Kingdom.ORCID http://orcid.org/0000-0002-9199-4201
Vytautus IvaskeviciusInstitute of Experimental Hematology and Transfusion medicine, University Hospital of Bonn, Bonn, 53127, Germany.
Diana ImhofPharmaceutical Biochemistry and Bioanalytics, Pharmaceutical Institute, University of Bonn, An der Immenburg 4, Bonn, 53121, Germany.ORCID http://orcid.org/0000-0003-4163-7334
Johannes OldenburgInstitute of Experimental Hematology and Transfusion medicine, University Hospital of Bonn, Bonn, 53127, Germany.
Arijit BiswasInstitute of Experimental Hematology and Transfusion medicine, University Hospital of Bonn, Bonn, 53127, Germany. arijit.biswas@ukb.uni-bonn.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dimeric FXIII-A

Indexed as

Enzyme ActivationBinding SitesCalciumFactor XIIIFactor XIIIaHEK293 CellsHumansModels, MolecularProtein BindingCalciumFactor XIIIFactor XIIIafactor XIII subunit A

Identifiers

PMID31383913
PMCPMC6683118

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.