Evidence map›Paper›PMID 31383781›Full record

ArticleSexually transmitted infections2020

Molecular diversity of

Helene C A Zondag, Akke R Cornelissen, Alje P van Dam, Sylvia M Bruisten

Open access · hybridAbstract read
In one paragraph

Article in Sexually transmitted infections, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Typing of Treponema pallidum in a Brazilian sample and follow-up of treatment using molecular assays.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  4. Article
  5. Article
  6. Molecular Characteristics of Macrolide Resistance inInfection and drug resistance · 2023
    Article
  7. Review
  8. Treponema pallidum SubspeciesMicrobiology spectrum · 2022
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Helene C A ZondagDepartment of Infectious Diseases, Public Health Laboratory, Public Health Service of Amsterdam, Amsterdam, The Netherlands h.zondag@amsterdamumc.nl.ORCID 0000-0001-9230-7488
Akke R CornelissenDepartment of Infectious Diseases, Public Health Laboratory, Public Health Service of Amsterdam, Amsterdam, The Netherlands.
Alje P van DamDepartment of Infectious Diseases, Public Health Laboratory, Public Health Service of Amsterdam, Amsterdam, The Netherlands.
Sylvia M BruistenDepartment of Infectious Diseases, Public Health Laboratory, Public Health Service of Amsterdam, Amsterdam, The Netherlands.
GGD Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe prevalence of syphilis, caused by the spirochete

methodsTPA DNA was extracted from 136 genital ulcer swab or skin lesions samples deriving from 135 patients diagnosed with syphilis in 2016 and 2017 at the Public Health Service in Amsterdam, the Netherlands. Molecular typing was done according to the enhanced CDC method (E-CDC), in which three genetic regions of the

resultsFull E-CDC strain types could be determined for 99/136 (73%) DNA samples, which tested positive in a diagnostic PCR targeting the

conclusionsA broad strain distribution was found. Few subtypes were clonally expanded, and most other subtypes were rare. Detection of the most prevalent strain type, 14d/g, is in concordance with other TPA typing studies. The high prevalence of genetic macrolide resistance indicates that azithromycin is not an alternative treatment option.

Indexed as

Genetic VariationGenotypeAdultAnti-Bacterial AgentsDrug Resistance, BacterialFemaleGenes, BacterialHumansMacrolidesMaleMicrobial Sensitivity TestsMiddle AgedMolecular TypingNetherlandsPrevalenceSyphilisAnti-Bacterial AgentsMacrolidesmacrolide resistancemolecular typingsyphilistreponema pallidum

Identifiers

PMID31383781
PMCPMC7231448
OpenAlexW2965961126

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.